Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations
A Bhowmik, TAR Seemungal, RJ Sapsford… - Thorax, 2000 - thorax.bmj.com
BACKGROUND Although it is presumed that exacerbations of chronic obstructive
pulmonary disease (COPD) are associated with increased airway inflammation, there is little …
pulmonary disease (COPD) are associated with increased airway inflammation, there is little …
Mechanisms of pollution‐induced airway disease: in vitro itudies in the upper and lower airways
…, RJ Sapsford, MA Abdelaziz, J Wang1, RJ Davies - Allergy, 1997 - Wiley Online Library
… Rusznak C, Devalia JL, Sapsford RJ, Davies RJ. Ozone… Bayram H, Devalia JL, Sapsford
RJ, Ohtoshi T, Davies RJ. … Calderon MA, Devalia JL, Prior AJ, Sapsford RJ, Davies RJ. A …
RJ, Ohtoshi T, Davies RJ. … Calderon MA, Devalia JL, Prior AJ, Sapsford RJ, Davies RJ. A …
Association of postoperative high-sensitivity troponin levels with myocardial injury and 30-day mortality among patients undergoing noncardiac surgery
…, J Spence, V Tandon, C Williams, RJ Sapsford… - Jama, 2017 - jamanetwork.com
Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …
Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations
…, JR Hurst, WR Perera, RJ Sapsford… - American journal of …, 2008 - atsjournals.org
Rationale: Frequent chronic obstructive pulmonary disease (COPD) exacerbations are a
major cause of hospital admission and mortality and are associated with increased airway …
major cause of hospital admission and mortality and are associated with increased airway …
Inflammatory changes, recovery and recurrence at COPD exacerbation
…, JR Hurst, TMA Wilkinson, RJ Sapsford… - European …, 2007 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) exacerbations are associated with increased
airway and systemic inflammation, though relationships between exacerbation recovery, …
airway and systemic inflammation, though relationships between exacerbation recovery, …
The Effect of Diesel Exhaust Particles on Cell Function and Release of Inflammatory Mediators from Human Bronchial Epithelial Cells In Vitro
H Bayram, JL Devalia, RJ Sapsford… - American journal of …, 1998 - atsjournals.org
Animal studies have reported that diesel exhaust particles (DEP), which constitute an important
fraction of particulate air pollution, lead to inflammation and/or damage of the airways. To …
fraction of particulate air pollution, lead to inflammation and/or damage of the airways. To …
Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease
M Roland, A Bhowmik, RJ Sapsford, TAR Seemungal… - Thorax, 2001 - thorax.bmj.com
BACKGROUND Endothelin (ET)-l is a bronchoconstrictor peptide produced in the airways. It
has been implicated in the pathogenesis of asthma and virally mediated airway …
has been implicated in the pathogenesis of asthma and virally mediated airway …
Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells
…, MM Abdelaziz, RJ Sapsford, RJ Davies - European …, 1995 - Eur Respiratory Soc
Although several studies have demonstrated that low-dose, long-term erythromycin treatment
is effective in the management of patients with chronic lower respiratory tract infections, …
is effective in the management of patients with chronic lower respiratory tract infections, …
Effect of ozone and nitrogen dioxide on the release of proinflammatory mediators from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic …
H Bayram, RJ Sapsford, MM Abdelaziz… - Journal of Allergy and …, 2001 - Elsevier
Background: Although studies have suggested that ozone (O 3 ) and nitrogen dioxide (NO 2
) may play a role in the pathogenesis of asthma, the underlying mechanisms are not clear. …
) may play a role in the pathogenesis of asthma, the underlying mechanisms are not clear. …
Association between complications and death within 30 days after noncardiac surgery
…, G Ackland, M Jacka, GH Guyatt, RJ Sapsford… - Cmaj, 2019 - Can Med Assoc
… Robert Sapsford received nonfinancial support in the form of a research nurse funded by
the National Institutes of Health Research, and lecture fees from Eli Lilly, MSD and Novo …
the National Institutes of Health Research, and lecture fees from Eli Lilly, MSD and Novo …