Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection
…, H Sakata, CM Maier, P Narasimhan… - Antioxidants & redox …, 2011 - liebertpub.com
Significant amounts of oxygen free radicals (oxidants) are generated during cerebral
ischemia/reperfusion, and oxidative stress plays an important role in brain damage after stroke. In …
ischemia/reperfusion, and oxidative stress plays an important role in brain damage after stroke. In …
[HTML][HTML] Risk factors for tuberculosis
P Narasimhan, J Wood, CR MacIntyre, D Mathai - Pulmonary …, 2013 - hindawi.com
The risk of progression from exposure to the tuberculosis bacilli to the development of active
disease is a two-stage process governed by both exogenous and endogenous risk factors. …
disease is a two-stage process governed by both exogenous and endogenous risk factors. …
Neuronal death/survival signaling pathways in cerebral ischemia
…, N Noshita, GW Kim, A Saito, T Hayashi, P Narasimhan… - NeuroRx, 2004 - Elsevier
Cumulative evidence suggests that apoptosis plays a pivotal role in cell death in vitro after
hypoxia. Apoptotic cell death pathways have also been implicated in ischemic cerebral injury …
hypoxia. Apoptotic cell death pathways have also been implicated in ischemic cerebral injury …
NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation
…, S Won Suh, S Joon Won, P Narasimhan… - Nature …, 2009 - nature.com
… Neurons incubated with either the complex III inhibitor antimycin 28 or the protonophore p-trifluoromethoxy
carbonyl cyanide phenyl hydrazone (FCCP) 10 showed a two- to threefold …
carbonyl cyanide phenyl hydrazone (FCCP) 10 showed a two- to threefold …
An analysis of traces from a production mapreduce cluster
…, J Tan, R Gandhi, P Narasimhan - 2010 10th IEEE/ACM …, 2010 - ieeexplore.ieee.org
MapReduce is a programming paradigm for parallel processing that is increasingly being used
for data-intensive applications in cloud computing environments. An understanding of the …
for data-intensive applications in cloud computing environments. An understanding of the …
Nonclassical monocytes in health and disease
PB Narasimhan, P Marcovecchio… - Annual review of …, 2019 - annualreviews.org
Monocytes are innate blood cells that maintain vascular homeostasis and are early responders
to pathogens in acute infections. There are three well-characterized classes of monocytes…
to pathogens in acute infections. There are three well-characterized classes of monocytes…
Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection
…, GS Kim, H Chen, CM Maier, P Narasimhan… - Molecular …, 2010 - Springer
Effective stroke therapies require recanalization of occluded cerebral blood vessels. However,
reperfusion can cause neurovascular injury, leading to cerebral edema, brain hemorrhage…
reperfusion can cause neurovascular injury, leading to cerebral edema, brain hemorrhage…
[HTML][HTML] Prevalence of oral lesions in relation to habits: Cross-sectional study in South India.
…, R Sowmya, PD Narasimhan… - Indian Journal of …, 2006 - journals.lww.com
BACKGROUND: Smoking, drinking and chewing tobacco product, common habits in India
have been positively associated with oral lesions. No study has been conducted in this part of …
have been positively associated with oral lesions. No study has been conducted in this part of …
Oxidative stress and neuronal death/survival signaling in cerebral ischemia
A Saito, CM Maier, P Narasimhan, T Nishi… - Molecular …, 2005 - Springer
It has been demonstrated by numerous studies that apoptotic cell death pathways are
implicated in ischemic cerebral injury in ischemia models in vivo. Experimental ischemia and …
implicated in ischemic cerebral injury in ischemia models in vivo. Experimental ischemia and …
Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin
J Liu, P Narasimhan, F Yu, PH Chan - Stroke, 2005 - Am Heart Assoc
Background and Purpose— Hypoxic preconditioning is an endogenous protection against
subsequent lethal hypoxia, but the mechanism involved is not understood. Hypoxia is …
subsequent lethal hypoxia, but the mechanism involved is not understood. Hypoxia is …