Aim To review multiorgan involvement and management in children with Down syndrome (DS).
Methods A literature review of articles from 1980 to 2019 using the MEDLINE interface of …

There is an abundance of antimicrobial peptides in cystic fibrosis (CF) lungs. Despite this,
individuals with CF are susceptible to microbial colonization and infection. In this study, we …

Rationale: Inflammation within the cystic fibrosis (CF) lung is mediated by inflammatory
chemokines, such as IL-8. IL-8 is protected from proteolytic degradation in the airways by binding …

… Liberation of p-nitroaniline was measured at 405 nm over a 5-min time period. NE activity in
the supernatants … Differences were considered significant when the P value was 0.05 or less. …

… CGM was reliable with a Bland-Altman agreement between CGM and OGTT of 0.81 mmol/l
(95% CI for bias ± 2.90 mmol/l) and good correlation between the two (r = 0.74–0.9; P < 0.01)…

… admissions per person (p = 0.023), a 112% increase in the number of respiratory exacerbations
per person (p = 0.042) and 48% increase in antimicrobial prescribing (p = 0.009) when …

… Walsh, AE Wood, and P. Greally, “Pleuropulmonary blastoma type I following resection of
incidentally found congenital lobar emphysema,” Irish Medical Journal, vol. 102, no. 7, article …

… with P. aeruginosa. Our objective was to examine the interactions between A. fumigatus and
P. … fumigatus and P. aeruginosa in the Galleria mellonella acute infection model showed that …

It is postulated that a vigorous host inflammatory response in the cystic fibrosis lung contributes
to lung injury. Tumour necrosis factor-alpha (TNF-alpha) may play a part in that process …

… 42.3,P=0.03; mean upper arm fat area 15.08 vs. 10.59,P=0.001; Shwachman score 43.7 vs.
32.1,P=0.001) were worse among CFLD participants than among CF controls. Cystic fibrosis-…