Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged >60 years). Efforts to develop a …

The global burden of disease caused by respiratory syncytial virus (RSV) is increasingly
recognised, not only in infants, but also in older adults (aged ≥65 years). Advances in …

Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections in
children. By the age of 1 year, 60%–70% of children have been infected by RSV. In addition…

Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of
morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with …

Seasonal influenza vaccine protects 60 to 90% of healthy young adults from influenza
infection. The immunological events that lead to the induction of protective antibody responses …

The analysis of patient blood transcriptional profiles offers a means to investigate the
immunological mechanisms relevant to human diseases on a genome-wide scale. In addition, such …

… Octavio Ramilo … As an example, Octavio Ramilo (Columbus, Ohio, USA) demonstrated an
alternative method that can be used for diagnosis: transcriptional analysis of whole blood from …

Each infectious agent represents a unique combination of pathogen-associated molecular
patterns that interact with specific pattern-recognition receptors expressed on immune cells. …

Patients with systemic lupus erythematosus (SLE) display a complex blood transcriptome
whose cellular origin is poorly resolved. Using single-cell RNA sequencing, we profiled ~…

Rationale: Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory
tract infections and hospitalizations in infants worldwide. Known risk factors, however, …