… Both isoforms share the same ligand and DNA binding domains, only differing from each
other in the N terminal region where RORγ is 21 amino acids longer. No known functional …

… This was submitted to hydrolysis and subsequent coupling with N 1 ,N 1 -dimethylethane-1,2-diamine
in the presence of HBTU and Et 3 N in DMSO to give the enantiomerically pure …

The further optimization of a recently disclosed series of inverse agonists of the nuclear
receptor RORC2 is described. Investigations into the left-hand side of compound 1, guided by X-…

We have modified the periplasmic Escherichia coli glucose/galactose binding protein (GBP)
and labelled with environmentally sensitive fluorophores to further explore its potential as a …

Open chest surgery in rodents requires assisted breathing and the most common approach
for ventilation is via an endotracheal tube. Even with well-trained operators the endotracheal …

Introduction: Classical theory suggests that asthma is driven by a Th2 inflammatory response
in the lung. Although this is true for many asthmatics it is becoming clear that in others, …

In this paper, we explore how highly visible users in the context of #BlackLivesMatter on
TikTok shape the narrative around Black victims of police brutality, the understanding of these …

Cachexia occurs frequently in patients with COPD and is a strong independent risk factor for
mortality. Our aim was to study the effect of Prednisolone and a ghrelin agonist on muscle …

This study looks at how mourning is expressed using the hashtag #grief on the social media
app TikTok using qualitative content analysis. In a dataset of 100 TikTok videos, this article …

the immediate aftermath of crisis events, there is a pressing demand among the public for
information about what is unfolding. In such moments “information holes” occur, people and …