This review describes the usefulness of monitoring the activity level of lactate dehydrogenase
(LDH) and its isoenzyme pattern as indicators of pathological conditions in the lungs, such …

Introduction The effectiveness of non-invasive positive pressure ventilation (NIV) in COPD
patients with prolonged hypercapnia after ventilatory support for acute respiratory failure (ARF…

… injury that strength values of 20 N or lower correspond to a grade 3 or less on the MRC
scale. The findings in thumb adduction (range 0–59 N, median 5 N) suggest that most of our …

During the six months from January–June 1994, 10 cases of severe and 11 of less severe
pulmonary infection caused by Pseudomonas aeruginosa were diagnosed in patients with …

… We conducted a nationwide, randomized controlled noninferiority trial, in which every HMV
center recruited 24 patients (home [n = 12] vs hospital [n = 12]) with a neuromuscular disease …

The effect on transcutaneous SaO 2 and transcutaneous carbon dixoide tension (PtCO 2 )
of eating was assessed in 44 patients with severe COPD (FEV 1 <50 percent) The SaO 2 , …

Background and aim of the work: Many sarcoidosis patients suffer from fatigue and sleep
disturbances. Recently, it was demonstrated that obstructive sleep apnea (OSA) is rather …

Background: Duchenne muscular dystrophy (DMD) is a progressive muscle disease. No
curative therapy is currently available, but in recent decades standards of care have improved. …

… ALS patients with cognitive impairment had a median survival time of 4.3 years (n = 18; 4.3
years, 95 % CI 2.69–5.81, p = 0.012; Fig. 2b). ALS patients with behavioral changes had a …

In the Netherlands we have an unique organisation of only 4 centres being responsible for
all patients who need Home Mechanical ventilation(HMV). Nationwide criteria for referral and …