Effects of neuromuscular electrical stimulation of muscles of ambulation in patients with chronic heart failure or COPD: a systematic review of the English-language …

MJH Sillen, CM Speksnijder, RMA Eterman… - Chest, 2009 - Elsevier
Introduction Despite optimal drug treatment, many patients with congestive heart failure (CHF)
or COPD still experience disabling dyspnea, fatigue, and exercise intolerance. They also …

[HTML][HTML] A narrative review on plasminogen activator inhibitor-1 and its (patho) physiological role: to target or not to target?

M Sillen, PJ Declerck - International journal of molecular sciences, 2021 - mdpi.com
Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of plasminogen
activators (PAs) and is therefore an important inhibitor of the plasminogen/plasmin system. …

[HTML][HTML] Metabolic and structural changes in lower-limb skeletal muscle following neuromuscular electrical stimulation: a systematic review

MJH Sillen, FME Franssen, HR Gosker, EFM Wouters… - PloS one, 2013 - journals.plos.org
Background Transcutaneous neuromuscular electrical stimulation (NMES) can be applied
as a complementary intervention to regular exercise training programs. A distinction can be …

New normative values for handgrip strength: results from the UK Biobank

MA Spruit, MJH Sillen, MTJ Groenen… - Journal of the American …, 2013 - Elsevier
… for right and left handgrip strength were derived from 224,830 and 224,852 individuals (54.2%
women; age: 55.0 [8.0] years; height: 169.0 [9.2] cm; body mass index: 26.9 [4.4] kg/m 2 ) …

Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: results from the DICES trial

MJH Sillen, FME Franssen, JML Delbressine, AW Vaes… - Thorax, 2014 - thorax.bmj.com
Rationale Strength training and neuromuscular electrical stimulation (NMES) improve lower-limb
muscle function in dyspnoeic individuals with chronic obstructive pulmonary disease (…

[HTML][HTML] Targeting PAI-1 in cardiovascular disease: structural insights into PAI-1 functionality and inhibition

M Sillen, PJ Declerck - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
… As the primary inhibitor of PAs, PAI-1 rapidly inactivates both tPA and uPA with second-order
rate constants between 10 6 and 10 7 M −1 s −1 following the basic mechanism applied to …

[HTML][HTML] Thrombin activatable fibrinolysis inhibitor (TAFI): an updated narrative review

M Sillen, PJ Declerck - International journal of molecular sciences, 2021 - mdpi.com
Thrombin activatable fibrinolysis inhibitor (TAFI), a proenzyme, is converted to a potent
attenuator of the fibrinolytic system upon activation by thrombin, plasmin, or the thrombin/…

Changes in lower limb muscle function and muscle mass following exercise-based interventions in patients with chronic obstructive pulmonary disease: a review of …

…, FME Franssen, W Derave, MJH Sillen… - Chronic Respiratory …, 2018 - journals.sagepub.com
Chronic obstructive pulmonary disease (COPD) patients often experience lower limb muscle
dysfunction and wasting. Exercise-based training has potential to improve muscle function …

An update on pulmonary rehabilitation techniques for patients with chronic obstructive pulmonary disease

…, MJ Sillen, B Hajian, M Sastry, M A. Spruit… - Expert review of …, 2020 - Taylor & Francis
Introduction: Pulmonary rehabilitation (PR) is one of the core components in the management
of patients with chronic obstructive pulmonary disease (COPD). In order to achieve the …

[HTML][HTML] The metabolic response during resistance training and neuromuscular electrical stimulation (NMES) in patients with COPD, a pilot study

MJH Sillen, PP Janssen, MA Akkermans… - Respiratory …, 2008 - Elsevier
Resistance training and transcutaneous neuromuscular electrical stimulation (NMES) are
new modalities in rehabilitation of severely disabled patients with chronic obstructive …