The epidermal growth factor receptor (EGFR) is activated by many ligands and belongs to a
family of tyrosine kinase receptors, including ErbB2, ErbB3, and ErbB4. These receptors are …

… Maria Sibilia … Karin Komposch wrote the manuscript under the supervision of Maria Sibilia,
who … Natarajan, A.; Wagner, B.; Sibilia, M. The EGF receptor is required for efficient liver …

Histone H3 lysine 9 methylation has been proposed to provide a major "switch" for the
functional organization of chromosomal subdomains. Here, we show that the murine Suv39h …

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is frequently
mutated or overexpressed in a large number of tumors such as carcinomas or glioblastoma. …

Mice and cells lacking the epidermal growth factor receptor (EGFR) were generated to
examine its physiological role in vivo. Mutant fetuses are retarded in growth and die at mid-…

Multipotent, self-renewing neural stem cells reside in the embryonic mouse telencephalic
germinal zone. Using anin vitroneurosphere assay for neural stem cell proliferation, we …

c-Jun is a major component of the heterodimeric transcription factor AP-1 and is essential
for embryonic development, as fetuses lacking Jun die at mid-gestation 1, 2 with impaired …

Initiation of pancreatic ductal adenocarcinoma (PDA) is definitively linked to activating
mutations in the KRAS oncogene. However, PDA mouse models show that mutant Kras …

Context: Coaches, athletic trainers (ATs), strength and conditioning specialists (SCSs), and
registered dietitians are common nutrition resources for athletes, but coaches, ATs, and …

It is established that tumor cell-derived VEGF acts on endothelial cells to promote angiogenesis
and tumor growth. Here, we demonstrate that in K5-SOS-dependent mouse skin tumors, …