Coronavirus disease 2019 (COVID-19) pneumonia is an evolving disease. We will focus on
the development of its pathophysiologic characteristics over time, and how these time-…

Several factors have been recognized as possible triggers of ventilator-induced lung injury (VILI).
The first is pressure (thus the ‘barotrauma’), then the volume (hence the ‘volutrauma’), …

… (M PAW ) [22]. The results regarding the effect of different I:E ratios are conflicting [22, 23].
Reported positive effects have been ascribed to the shortening of expiratory time, increased M …

Background In the acute respiratory distress syndrome (ARDS), positive end-expiratory
pressure (PEEP) may decrease ventilator-induced lung injury by keeping lung regions open that …

Objective To determine the prevalence and mortality of ICU patients with severe sepsis in
Germany, with consideration of hospital size. Design Prospective, observational, cross-…

Purpose We hypothesized that the ventilator-related causes of lung injury may be unified in
a single variable: the mechanical power. We assessed whether the mechanical power …

Rationale: Tidal volume and plateau pressure limitation decreases mortality in acute
respiratory distress syndrome. Computed tomography demonstrated a small, normally aerated …

… carbon dioxide removal was initiated by using a modified continuous veno-venous
hemofiltration system equipped with a membrane lung with a total membrane surface of 0.33 m 2 (…

… Before each CT scanning, a recruitment maneuver was performed (see additional Methods …
O, Gandini G, Herrmann P, Mascia L, Quintel M, et al. Tidal hyperinflation during low tidal …

BACKGROUND: Rapid establishment of a patent airway in ill or injured patients is a priority
for prehospital rescue personnel. Out-of-hospital tracheal intubation can be challenging. …