The care of patients with difficult‐to‐control asthma (“difficult asthma”) is challenging and
costly. Despite high‐intensity asthma treatment, these patients experience poor asthma control …

Oral corticosteroids (OCS) are frequently used for asthma treatment. This medication is highly
effective for both acute and chronic diseases, but evidence indicates that indiscriminate …

The potential of precision medicine in allergy and asthma has only started to be explored. A
significant clarification in the pathophysiology of rhinitis, chronic rhinosinusitis, asthma, food …

BACKGROUND: Severe asthma causes the majority of asthma morbidity. Understanding
mechanisms that contribute to the development of severe disease is important. OBJECTIVE: …

Transient receptor potential vanniloid-1 (TRPV-1) mediates the cough response induced by
the pepper extract capsaicin and is expressed in sensory nerves that innervate the airway …

… No new consequences of long-term eosinophil depletion occurred, and the incidence of
other adverse events, including opportunistic infections, were similar during the second year. …

… We showed that at the higher dose of 10 −6 M of dexamethasone, there was less reduction
of cytokine release in cells from patients with severe asthma compared that from patients with …

… Figure 2 Effect of (A) dexamethasone 10 −6 M and (B) dexamethasone 10 −8 M on the
suppression of release of 10 cytokines from alveolar macrophages stimulated by …

Background Clinical characteristics of the international population with severe asthma are
unknown. Intercountry comparisons are hindered by variable data collection within regional …

Background A multidisciplinary collaboration investigated the world's largest, most catastrophic
epidemic thunderstorm asthma event that took place in Melbourne, Australia, on Nov 21, …