Background The risk of tuberculosis outbreaks among people fleeing hardship for refuge in
Europe is heightened. We describe the cross-border European response to an outbreak of …

Objectives Culture-based assays are currently the reference standard for drug susceptibility
testing for Mycobacterium tuberculosis. They provide good sensitivity and specificity but are …

… Isolates with the M phenotype were the least susceptible to telithromycin, a new ketolide.
The mef(A) gene was found in the isolates with the M phenotype and the erm(B) gene in the …

In this study, the performances of two matrix-assisted laser desorption ionization–time of
flight mass spectrometry (MALDI-TOF MS) systems, MALDI Biotyper (Bruker Daltonics) and …

Reliable distinction of Streptococcus pneumoniae and viridans group streptococci is
important because of the different pathogenic properties of these organisms. Differentiation …

Background .We conducted a 5-year follow-up study on the persistence of pertussis-specific
antibody and cell-mediated immunity after booster immunization of adolescents aged 11–13 …

Bordetella holmesii is a Gram-negative bacterium first identified in 1995. It can cause
pertussis-like symptoms in humans. B. holmesii contains insertion sequences IS481 and IS1001, …

Alpha-hemolytic streptococci are very difficult to identify by phenotypic methods. In this study,
a pyrosequencing method for the identification of streptococcal species based on two …

Treatment of multidrug-resistant tuberculosis (MDR-TB) is a global challenge requiring long
treatment with costly drugs. We assessed treatment combinations, outcome and the utility of …

A pyrosequencing method for detection and quantification of macrolide resistance mutations
at positions 2058 and 2059 (Escherichia coli numbering) of the 23S rRNA gene is described…