Sudden cardiac death is among the most common causes of cardiovascular death in
developed countries. The majority of sudden cardiac deaths are caused by acute ventricular …

A prolonged QT interval is an important risk factor for ventricular arrhythmias and sudden
cardiac death. QT prolongation can be caused by drugs. There are multiple risk factors for drug-…

Spirometric measures of lung function are heritable traits that reflect respiratory health and
predict morbidity and mortality. We meta-analyzed genome-wide association studies for two …

QT interval duration, reflecting myocardial repolarization on the electrocardiogram, is a
heritable risk factor for sudden cardiac death and drug-induced arrhythmias. We conducted a …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

The QRS interval, from the beginning of the Q wave to the end of the S wave on an
electrocardiogram, reflects ventricular depolarization and conduction time and is a risk factor for …

Elevated resting heart rate is associated with greater risk of cardiovascular disease and
mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 …

The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a
heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac …

Background Immune checkpoint inhibitor-associated acute kidney injury (ICPi-AKI) has emerged
as an important toxicity among patients with cancer. Methods We collected data on 429 …

Sudden cardiac death (SCD) is a major health burden and is primarily caused by ventricular
arrhythmias. Currently, the most well-known marker for the risk of ventricular arrhythmias is …