[HTML][HTML] The atlas of inflammation resolution (AIR)

…, M Dubourdeau, SS Gupta, P Schopohl, M Hoch… - Molecular aspects of …, 2020 - Elsevier
Acute inflammation is a protective reaction by the immune system in response to invading
pathogens or tissue damage. Ideally, the response should be localized, self-limited, and …

LC–MS/MS method for rapid and concomitant quantification of pro-inflammatory and pro-resolving polyunsaturated fatty acid metabolites

…, N Vergnolle, J Bertrand-Michel, M Dubourdeau… - … of Chromatography B, 2013 - Elsevier
Lipid autacoids derived from n-3/n-6 polyunsaturated fatty acids (PUFA) are some of the
earliest signals triggered by an inflammatory reaction. They are acting also as essential …

Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4

M Dubourdeau, R Athman, V Balloy… - The Journal of …, 2006 - journals.aai.org
… Briefly, freshly harvested conidia (2 × 10 8 per 10 ml of 0.05 M sodium carbonate buffer (pH
10.2)) were incubated with FITC at a final concentration of 0.1 mg/ml at 37C for 1 h and …

Quantification and potential functions of endogenous agonists of transient receptor potential channels in patients with irritable bowel syndrome

…, C Rolland, J Bertrand, W Liedtke, M Dubourdeau… - Gastroenterology, 2015 - Elsevier
… In contrast, exposure of those neurons to lipids from biopsies of IBS-M patients had no
effect on calcium mobilization (Figure 4C). Pretreatment of neurons with a TRPV4 antagonist (…

Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolution

…, A Poupon, JF Mosnier, G Chêne, M Dubourdeau… - Science …, 2021 - science.org
Resolution of inflammation is elicited by proresolving lipids, which activate GPCRs to induce
neutrophil apoptosis, reduce neutrophil tissue recruitment, and promote macrophage …

[PDF][PDF] PPARγ promotes mannose receptor gene expression in murine macrophages and contributes to the induction of this receptor by IL-13

A Coste, M Dubourdeau, MD Linas, S Cassaing… - Immunity, 2003 - cell.com
… hr both in the presence of 1 M 15dPGJ2 (J2), 5 M ciglitazone (cigli), 5 M rosiglitazone (rosi), …
phagocytize Plasmodium falcipresence of 1 M 15d-PGJ2, 5 M ciglitazone, 5 M rosiglitazone, …

[HTML][HTML] Resolvin D1 reduces lung infection and inflammation activating resolution in cystic fibrosis

…, M Dubourdeau, P Moretti, M Di Sabatino… - Frontiers in …, 2020 - frontiersin.org
Non-resolving lung inflammation and Pseudomonas aeruginosa infections are the underlying
cause of morbidity and mortality in cystic fibrosis (CF). The endogenous lipid mediator …

Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis

…, M Dubourdeau, JP Latgé, P Ave, M Huerre… - Cellular …, 2008 - Wiley Online Library
… Deletion of both of these isocitrate lyases from the M. tuberculosis genome led to the
rapid elimination of bacteria from the lungs and an impairment of intracellular replication (Munoz-…

Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder

C Augé, G Chene, M Dubourdeau… - European journal of …, 2013 - Elsevier
This work aimed at establishing the relevance of using the in vivo model of cyclophosphamide
(CYP)-induced bladder inflammation in rats for in vivo pharmacological studies. …

Long chain fatty acids and related pro-inflammatory, specialized pro-resolving lipid mediators and their intermediates in preterm human milk during the first month of …

…, V Baillif, E Van Goethem, M Dubourdeau… - … and Essential Fatty …, 2017 - Elsevier
This study aimed to measure longitudinal quantities of the long chain fatty acids, their biologically
active terminal metabolites and related intermediates (also called oxylipins) in preterm …