The global breast cancer burden: variations in epidemiology and survival
…, R Haidinger, CA Hudis, H Khaled, MC Liu… - Clinical breast …, 2005 - Elsevier
Breast cancer is the most common type of cancer and the most common cause of cancer-related
mortality among women worldwide. However, the burden is not evenly distributed, and, …
mortality among women worldwide. However, the burden is not evenly distributed, and, …
The properties of high-dimensional data spaces: implications for exploring gene and protein expression data
High-throughput genomic and proteomic technologies are widely used in cancer research
to build better predictive models of diagnosis, prognosis and therapy, to identify and …
to build better predictive models of diagnosis, prognosis and therapy, to identify and …
Statistical theory of quantization
B Widrow, I Kollar, MC Liu - IEEE Transactions on …, 1996 - ieeexplore.ieee.org
The effect of uniform quantization can often be modeled by an additive noise that is uniformly
distributed, uncorrelated with the input signal, and has a white spectrum. This paper …
distributed, uncorrelated with the input signal, and has a white spectrum. This paper …
[HTML][HTML] Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
…, H Liu, Q Liu, M Lopatin, T Maddala, MC Maher… - Annals of …, 2020 - Elsevier
Background Early cancer detection could identify tumors at a time when outcomes are
superior and treatment is less morbid. This prospective case-control sub-study (from …
superior and treatment is less morbid. This prospective case-control sub-study (from …
[HTML][HTML] Adjuvant trastuzumab in HER2-positive breast cancer
…, M Pawlicki, T Pinter, V Valero, MC Liu… - New England journal …, 2011 - Mass Medical Soc
Background Trastuzumab improves survival in the adjuvant treatment of HER-positive
breast cancer, although combined therapy with anthracycline-based regimens has been …
breast cancer, although combined therapy with anthracycline-based regimens has been …
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a …
…, YH Im, L Roman, LM Tseng, MC Liu… - The lancet …, 2012 - thelancet.com
Background Studies with pertuzumab, a novel anti-HER2 antibody, show improved efficacy
when combined with the established HER2-directed antibody trastuzumab in breast cancer …
when combined with the established HER2-directed antibody trastuzumab in breast cancer …
[HTML][HTML] Mepolizumab treatment in patients with severe eosinophilic asthma
Background Some patients with severe asthma have frequent exacerbations associated with
persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled …
persistent eosinophilic inflammation despite continuous treatment with high-dose inhaled …
Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004
Background Vitamin D insufficiency is associated with suboptimal health. The prevalence of
vitamin D insufficiency may be rising, but population-based trends are uncertain. We sought …
vitamin D insufficiency may be rising, but population-based trends are uncertain. We sought …
Comet 81P/Wild 2 under a microscope
The Stardust spacecraft collected thousands of particles from comet 81P/Wild 2 and returned
them to Earth for laboratory study. The preliminary examination of these samples shows …
them to Earth for laboratory study. The preliminary examination of these samples shows …
[HTML][HTML] Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set
…, KN Kurtzman, MV Seiden, C Swanton, MC Liu - Annals of …, 2021 - Elsevier
Background A multi-cancer early detection (MCED) test used to complement existing screening
could increase the number of cancers detected through population screening, potentially …
could increase the number of cancers detected through population screening, potentially …