… In this section, we will refer to tidal ∆P L , ignoring for sake of simplicity the fraction of ∆P L
due to positive end-expiratory pressure (PEEP). As the changes in lung volume and chest wall …

Monitoring plays an important role in the current management of patients with acute respiratory
failure but sometimes lacks definition regarding which 'signals' and 'derived variables' …

… expiratory flow is only 0.25 L/s, the patient can exhale only 0.5 L (half of the … 1 L would be
reached when the increase in lung volume resulted in a maximum mean expiratory flow of 0.5 L/…

Because animal studies have demonstrated that mechanical ventilation at high volume and
pressure can be deleterious to the lungs, limitation of airway pressure, allowing hypercapnia …

The duration of spontaneous breathing trials before extubation has been set at 2 h in research
studies, but the optimal duration is not known. We conducted a prospective, multicenter …

Context Post hoc analysis of a previous trial has suggested that prone positioning may improve
survival in patients with severe hypoxemia and with acute respiratory distress syndrome (…

Purpose While our understanding of the pathogenesis and management of acute respiratory
distress syndrome (ARDS) has improved over the past decade, estimates of its incidence …

Objective: To determine whether continuous subglottic aspiration prevents nosocomial
pneumonia in mechanically ventilated patients. Design: A randomized, controlled, blinded study. …

Rationale: Ventilation in the prone position for about 7 h/d in patients with acute respiratory
distress syndrome (ARDS), acute lung injury, or acute respiratory failure does not decrease …

Purpose This study aimed to assess the prevalence and time course of asynchronies during
mechanical ventilation (MV). Methods Prospective, noninterventional observational study of …