Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …

… The function of the corneal endothelium is maintained by the function of the Na + , K + …
tight junction proteins and functional Na + , K + ATPase pumps were maintained after recovery …

Adipose tissue secretes proteins referred to as adipokines, many of which promote inflammation
and disrupt glucose homeostasis. Here we show that secreted frizzled-related protein 5 (…

Hepatic tissue engineering using primary hepatocytes has been considered a valuable new
therapeutic modality for several classes of liver diseases. Recent progress in the …

Rac is a small GTPase of the Rho family that mediates stimulus-induced actin cytoskeletal
reorganization to generate lamellipodia 1 , 2 , 3 , 4 , 5 . Little is known about the signalling …

The actin cytoskeleton undergoes extensive remodeling during cell morphogenesis and
motility. The small guanosine triphosphatase Rho regulates such remodeling, but the …

Obesity-related disorders are associated with the development of ischemic heart disease.
Adiponectin is a circulating adipose-derived cytokine that is downregulated in obese …

Background— High-sensitive C-reactive protein (hs-CRP) is a well-known risk factor for
coronary artery disease (CAD). Recently, we have demonstrated that adiponectin served as an …

Human heat shock protein 60 (hsp60) elicits a potent proinflammatory response in cells of the
innate immune system and therefore has been proposed as a danger signal of stressed or …

Adiponectin is one of the key molecules in the metabolic syndrome, and its concentration is
decreased in obesity, type-2 diabetes, and coronary artery disease. Genetic investigation …