We performed a genome-wide association study of non-Hispanic, white individuals with fibrotic
idiopathic interstitial pneumonias (IIPs; n = 1,616) and controls (n = 4,683), with follow-up …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal
fibrotic lung disease characterized by profound changes in epithelial cell phenotype and …

Importance Current prediction models of mortality in idiopathic pulmonary fibrosis (IPF),
which are based on clinical and physiological parameters, have modest value in predicting …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology
with a variable and unpredictable course. Objectives: The aim of this study was to identify and …

Rationale: The molecular mechanisms underlying acute exacerbations of idiopathic pulmonary
fibrosis (IPF) are poorly understood. We studied the global gene expression signature of …

Laser systems permit very high energy radiation of a single wavelength to be focused on a
tiny spot, and have found application in many areas of engineering. They are also currently …

We aimed to identify peripheral blood mononuclear cell (PBMC) gene expression profiles
predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) by performing microarray …

Usual interstitial pneumonia (UIP) is a specific histopathologic pattern of interstitial lung
fibrosis that may be idiopathic or secondary to autoimmune diseases and environmental …

Background Lysyl oxidase-like 2 (LOXL2) catalyses collagen cross-linking and is implicated
in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The aim of this study was to …

Background Although the etiology of idiopathic pulmonary fibrosis (IPF) remains perplexing,
adaptive immune activation is evident among many afflicted patients. Repeated cycles of …