Natural history of COVID-19 and therapeutic options
Introduction: COVID-19 presents benign forms in young patients who frequently present with
anosmia. Infants are rarely infected, while severe forms occur in patients over 65 years of …
anosmia. Infants are rarely infected, while severe forms occur in patients over 65 years of …
Human mast cell tryptase in biology and medicine
J Vitte - Molecular immunology, 2015 - Elsevier
The most abundant prestored enzyme of human mast cell secretory granules is the serine-protease
tryptase. In humans, there are four tryptase isoforms, but only two of them, namely …
tryptase. In humans, there are four tryptase isoforms, but only two of them, namely …
[HTML][HTML] The SNARE machinery in mast cell secretion
A Lorentz, A Baumann, J Vitte, U Blank - Frontiers in immunology, 2012 - frontiersin.org
Mast cells are known as inflammatory cells which exert their functions in allergic and
anaphylactic reactions by secretion of numerous inflammatory mediators. During an allergic …
anaphylactic reactions by secretion of numerous inflammatory mediators. During an allergic …
A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition
Mutations of the spastin gene (Sp) are responsible for the most frequent autosomal dominant
form of spastic paraplegia, a disease characterized by the degeneration of corticospinal …
form of spastic paraplegia, a disease characterized by the degeneration of corticospinal …
Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria
…, AO Stemmer‐Rachamimov, J Vitte… - American journal of …, 2013 - Wiley Online Library
Schwannomatosis is the third major form of neurofibromatosis and is characterized by the
development of multiple schwannomas in the absence of bilateral vestibular schwannomas. …
development of multiple schwannomas in the absence of bilateral vestibular schwannomas. …
Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis
Background Coronavirus disease 2019 (COVID-19) clinical expression is pleiomorphic,
severity is related to age and comorbidities such as diabetes and hypertension, and …
severity is related to age and comorbidities such as diabetes and hypertension, and …
Component‐resolved diagnosis with commercially available D. pteronyssinus Der p 1, Der p 2 and Der p 10: relevant markers for house dust mite allergy
…, D Charpin, P Bongrand, J Vitte - Clinical & …, 2012 - Wiley Online Library
Background Commercially available house dust mite components may improve routine
testing of allergic patients. Objective To establish the prevalence and serum levels of IgE to …
testing of allergic patients. Objective To establish the prevalence and serum levels of IgE to …
A granulocytic signature identifies COVID-19 and its severity
Background An unbiased approach to SARS-CoV-2–induced immune dysregulation has not
been undertaken so far. We aimed to identify previously unreported immune markers able …
been undertaken so far. We aimed to identify previously unreported immune markers able …
Refined characterization of the expression and stability of the SMN gene products
J Vitte, C Fassier, FD Tiziano, C Dalard, S Soave… - The American journal of …, 2007 - Elsevier
Spinal muscular atrophy (SMA) is characterized by degeneration of lower motor neurons and
caused by mutations of the SMN1 gene. SMN1 is duplicated in a homologous gene called …
caused by mutations of the SMN1 gene. SMN1 is duplicated in a homologous gene called …
Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis
To date, the Covid-19 pandemic affected more than 18 million individuals and caused more
than 690, 000 deaths. Its clinical expression is pleiomorphic and severity is related to age …
than 690, 000 deaths. Its clinical expression is pleiomorphic and severity is related to age …