Introduction: Large anatomical variations can be observed during the treatment course
intensity-modulated radiotherapy (IMRT) for head and neck cancer (HNC), leading to potential …

Radiotherapy (RT) is one of the main components in the treatment of cancer. The better
understanding of the immune mechanisms associated with tumor establishment and how RT …

Background: Deformable image registration (DIR) is increasingly used in the field of radiation
therapy (RT) to account for anatomical deformations. The aims of this paper are to describe …

Background Fabry’s disease, an X-linked disorder of lysosomal α-galactosidase deficiency,
leads to substrate accumulation in multiple organs. Migalastat, an oral pharmacologic …

This paper relates the post-analysis of the first edition of the HEad and neCK TumOR (HECKTOR)
challenge. This challenge was held as a satellite event of the 23rd International …

Background Fabry disease is an X-linked lysosomal storage disorder caused by GLA mutations,
resulting in α-galactosidase (α-Gal) deficiency and accumulation of lysosomal substrates…

Purpose: Fabry disease is an X-linked lysosomal storage disorder caused by mutations in
the α-galactosidase A gene. Migalastat, a pharmacological chaperone, binds to specific …

The 2–5A system contributes to the antiviral effect of interferons through the synthesis of 2–5A
and its activation of the ribonuclease, RNase L. RNase L degrades viral and cellular RNA …

Multicenter studies are needed to demonstrate the clinical potential value of radiomics as a
prognostic tool. However, variability in scanner models, acquisition protocols and …

Plants can alter biotic and abiotic soil characteristics in ways that feedback to change the
performance of that same plant species relative to co‐occurring plants. Most evidence for this …