Objective Current guidelines recommend screening for latent tuberculosis infection (LTBI)
with a tuberculin skin test (TST) or interferon gamma release assay (IGRA), or both. Many also …

Background Screening for tuberculosis (TB) infection often includes QuantiFERON-TB Gold
Plus (QFT) testing. Previous studies showed that two-thirds of patients with negative QFT …

Background QuantiFERON (QFT) results near the cut-off are subject to debate. We aimed to
investigate which borderline QFT results were due to Mycobacterium tuberculosis (Mtb)-…

Interferon-γ release assays (IGRAs) such as Quantiferon (QFT) that detect T-cell responses
to antigens specific for Mycobacterium tuberculosis (MTB) have superior specificity to the …

Background Several radiological features have been reported in association with latent
tuberculosis infection (LTBI) but it has not been studied which are specific. The aim of this study …

Patients who are eligible for treatment with immunosuppressive drugs such as antagonists of
tumour necrosis factor (TNF)-α must be screened for latent tuberculosis infection (LTBI), as …

While postnatal toxoplasmosis in immune-competent patients is generally considered a self-limiting
and mild illness, it has been associated with a variety of more severe clinical …

To diagnose or exclude tuberculosis can be challenging because of the varied clinical signs
and the limitations of diagnostic tests. Tuberculosis diagnosis has evolved from autopsies …

… We thank Sandra Arend and Jonathan Uzorka for their thoughtful comments on our study.Our
study population included people from countries where a BCG vaccine is administered at …

Screening for latent tuberculosis infection (LTBI) is indicated before immunosuppressive
therapies but is complicated by lack of a gold standard and limited by, eg, immunosuppression. …