Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS in which an
unrelenting attack from the innate and adaptive arms of the immune system results in extensive …

Experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis, can be
induced by immunization with a number of myelin antigens. In particular, myelin …

The role of lung epithelial stem cells in maintenance and repair of the adult lung is ill-defined,
and their identity remains contentious because of the lack of definitive markers for their …

Inhibitors associated with CNS myelin are thought to be important in the failure of axons to
regenerate after spinal cord injury and in other neurodegenerative disorders. Here we show …

Originally identified as a marker specifying murine hematopoietic stem cells, the Sca-1
antigen has since been shown to be differentially expressed by candidate stem cells in tissues …

Chronic obstructive pulmonary disease (COPD) will soon be the third most common cause
of death globally. Despite smoking cessation, neutrophilic mucosal inflammation persistently …

Rationale: Declining lung function in patients with interstitial lung disease is accompanied
by epithelial remodeling and progressive scarring of the gas-exchange region. There is a …

… of Melbourne early career research grant to JL McQualter. We apologize to our colleagues
whose work we have been unable to cite comprehensively because of space constraints. …

Recent studies have implicated keratin 5 (KRT5) + cells in repopulation of damaged lung
tissue following severe H1N1 influenza virus infection. However, the origins of the cells …

Air spaces of the mammalian lung are lined by a specialized epithelium that is maintained
by endogenous progenitor cells. Within bronchioles, the abundance and distribution of …