User profiles for J. D. Lourenço
Juliana Dias LourençoFaculdade de Medicina, Universidade de São Paulo Verified email at usp.br Cited by 548 |
[HTML][HTML] Extracellular matrix component remodeling in respiratory diseases: what has been found in clinical and experimental studies?
Changes in extracellular matrix (ECM) components in the lungs are associated with the
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease (…
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease (…
[HTML][HTML] Th17/Treg imbalance in chronic obstructive pulmonary disease: clinical and experimental evidence
The imbalance between pro- and anti-inflammatory immune responses mediated by Th17
and Treg cells is deeply involved in the development and progression of inflammation in …
and Treg cells is deeply involved in the development and progression of inflammation in …
[HTML][HTML] Th17/Treg imbalance in COPD progression: A temporal analysis using a CS-induced model
Background The imbalance between pro- and anti-inflammatory immune responses plays a
pivotal role in chronic obstructive pulmonary disease (COPD) development and progression…
pivotal role in chronic obstructive pulmonary disease (COPD) development and progression…
Aerobic exercise attenuates pulmonary inflammation induced by Streptococcus pneumoniae
…, FM Almeida, JD Lourenço… - Journal of applied …, 2014 - journals.physiology.org
Aerobic exercise has been recognized as a stimulator of the immune system, but its effect
on bacterial infection has not been extensively evaluated. We studied whether moderate …
on bacterial infection has not been extensively evaluated. We studied whether moderate …
[HTML][HTML] Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins
LEF Silva, JD Lourenço, KR Silva, FPR Santana… - Scientific reports, 2020 - nature.com
Th17/Treg imbalance contributes to chronic obstructive pulmonary disease (COPD) development
and progression. However, intracellular signaling by suppressor of cytokine signaling (…
and progression. However, intracellular signaling by suppressor of cytokine signaling (…
[HTML][HTML] The Th17/Treg cytokine imbalance in chronic obstructive pulmonary disease exacerbation in an animal model of cigarette smoke exposure and …
We proposed an experimental model to verify the Th17/Treg cytokine imbalance in COPD
exacerbation. Forty C57BL/6 mice were exposed to room air or cigarette smoke (CS) (12 ± 1 …
exacerbation. Forty C57BL/6 mice were exposed to room air or cigarette smoke (CS) (12 ± 1 …
The deleterious effects of smoking in bone mineralization and fibrillar matrix composition
AP Barbosa, JD Lourenço, JJM Junqueira… - Life sciences, 2020 - Elsevier
Introduction This study aimed to verify the effects of cigarette smoke exposure in bone
mineralization and fibrillar matrix composition as well as in bone healing after tibial fracture …
mineralization and fibrillar matrix composition as well as in bone healing after tibial fracture …
[HTML][HTML] A Treatment with a Protease Inhibitor Recombinant from the Cattle Tick (Rhipicephalus Boophilus microplus) Ameliorates Emphysema in Mice
JD Lourenco, LP Neves, CR Olivo, A Duran… - PLoS …, 2014 - journals.plos.org
Aims To determine whether a serine protease inhibitor treatment can prevent or minimize
emphysema in mice. Methods C57BL/6 mice were subjected to porcine pancreatic elastase (…
emphysema in mice. Methods C57BL/6 mice were subjected to porcine pancreatic elastase (…
[HTML][HTML] Th17/Treg-related intracellular signaling in patients with chronic obstructive pulmonary disease: Comparison between local and systemic responses
Th17/Treg imbalance plays a pivotal role in COPD development and progression. We aimed
to assess Th17/Treg-related intracellular signaling at different COPD stages in local and …
to assess Th17/Treg-related intracellular signaling at different COPD stages in local and …
[HTML][HTML] Chronic exposure to diesel particles worsened emphysema and increased M2-like phenotype macrophages in a PPE-induced model
…, JB Kohler, JT Ito, LE de França Silva, JD Lourenço… - Plos one, 2020 - journals.plos.org
Chronic exposure to ambient levels of air pollution induces respiratory illness exacerbation
by increasing inflammatory responses and apoptotic cells in pulmonary tissues. The …
by increasing inflammatory responses and apoptotic cells in pulmonary tissues. The …