Changes in extracellular matrix (ECM) components in the lungs are associated with the
progression of respiratory diseases, such as asthma, chronic obstructive pulmonary disease (…

The imbalance between pro- and anti-inflammatory immune responses mediated by Th17
and Treg cells is deeply involved in the development and progression of inflammation in …

Background The imbalance between pro- and anti-inflammatory immune responses plays a
pivotal role in chronic obstructive pulmonary disease (COPD) development and progression…

Aerobic exercise has been recognized as a stimulator of the immune system, but its effect
on bacterial infection has not been extensively evaluated. We studied whether moderate …

Th17/Treg imbalance contributes to chronic obstructive pulmonary disease (COPD) development
and progression. However, intracellular signaling by suppressor of cytokine signaling (…

We proposed an experimental model to verify the Th17/Treg cytokine imbalance in COPD
exacerbation. Forty C57BL/6 mice were exposed to room air or cigarette smoke (CS) (12 ± 1 …

Introduction This study aimed to verify the effects of cigarette smoke exposure in bone
mineralization and fibrillar matrix composition as well as in bone healing after tibial fracture …

Aims To determine whether a serine protease inhibitor treatment can prevent or minimize
emphysema in mice. Methods C57BL/6 mice were subjected to porcine pancreatic elastase (…

Th17/Treg imbalance plays a pivotal role in COPD development and progression. We aimed
to assess Th17/Treg-related intracellular signaling at different COPD stages in local and …

Chronic exposure to ambient levels of air pollution induces respiratory illness exacerbation
by increasing inflammatory responses and apoptotic cells in pulmonary tissues. The …