Objectives To systematically review studies investigating the prevalence of antibiotic resistance
in urinary tract infections caused by Escherichia coli in children and, when appropriate, …

How do we know whether a particular treatment really works? How reliable is the evidence?
And how do we ensure that research into medical treatments best meets the needs of …

The communication of risk is a central activity in clinical genetics, with genetic health
professionals encouraging the dissemination of relevant information by individuals to their at-risk …

… Lord Brougham seems to have known him well*, and in 1812 we find Ricardo inviting
Malthus to dine with him and Thornton, a dinner party which the busy Thornton asks to have …

The decision to sequester CO 2 in the deep ocean should ultimately be based not only upon
what would happen to deep sea marine biota but also upon what would happen to surface …

Background Mammography screening can reduce breast cancer mortality. However, most
women are unaware that inconsequential disease can also be detected by screening, leading …

The discourse on teacher quality has centered on issues of teacher knowledge and teacher
skill, yet a third element that is central to all professional standards is teacher dispositions. …

We use reanalysis data to investigate the daily co-variability of wind and solar irradiance in
Britain, and its implications for renewable energy supply balancing. The joint distribution of …

Resistance exercise is difficult to quantify owing to its inherent complexity with numerous
training variables contributing to the training dose (type of exercise, load lifted, training volume, …

UKCP18 provides a new set of climate projections and tools to access climate data. The
major innovations in UKCP18 include the use of new observations of weather and climate, …