New trends in fast liquid chromatography for food and environmental analysis

O Núñez, H Gallart-Ayala, CPB Martins… - Journal of Chromatography …, 2012 - Elsevier
There is an increasing need for applications in food and environmental areas able to cope
with a large number of analytes in very complex matrices. The new analytical procedures …

Recent advances in LC-MS analysis of food-packaging contaminants

H Gallart-Ayala, O Núñez, P Lucci - TrAC Trends in Analytical Chemistry, 2013 - Elsevier
The supply of safe and high-quality foodstuffs relies on the efficient protection of food from
deterioration. However, all food-packaging materials can release small amounts of their …

PERK is a critical metabolic hub for immunosuppressive function in macrophages

…, H Zhao, Y Wang, HY Chen, H Gallart-Ayala… - Nature …, 2022 - nature.com
… To confirm this, we stimulated BMDMs with the T H 2 cytokine IL-4 or assessed TAMs from
animals bearing B16-F10 melanoma. We found that both IL-4-stimulated macrophages and …

Hyperglycemia induces trained immunity in macrophages and their precursors and promotes atherosclerosis

…, AT Braithwaite, T Krausgruber, H Gallart-Ayala… - Circulation, 2021 - Am Heart Assoc
Background: Cardiovascular risk in diabetes remains elevated despite glucose-lowering
therapies. We hypothesized that hyperglycemia induces trained immunity in macrophages, …

Analysis of bisphenols in soft drinks by on-line solid phase extraction fast liquid chromatography–tandem mass spectrometry

H Gallart-Ayala, E Moyano, MT Galceran - Analytica Chimica Acta, 2011 - Elsevier
In this study, an automated on-line solid-phase extraction coupled to fast liquid
chromatography–tandem mass spectrometry (on-line SPE fast LC–MS/MS) method was developed …

Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity

G Di Conza, CH Tsai, H Gallart-Ayala, YR Yu… - Nature …, 2021 - nature.com
… After 24 h, the medium was changed and the virus was collected at 48 h and 72 h post-transfection.
Retrovirus was added to BMDM culture medium (20% L929 in DMEM) in the …

Metabolomics meets lipidomics: Assessing the small molecule component of metabolism

H GallartAyala, T Teav, J Ivanisevic - BioEssays, 2020 - Wiley Online Library
Metabolomics, including lipidomics, is emerging as a quantitative biology approach for the
assessment of energy flow through metabolism and information flow through metabolic …

Immunoediting instructs tumor metabolic reprogramming to support immune evasion

…, KC Kao, H Imrichova, L Duan, H Gallart-Ayala… - Cell metabolism, 2023 - cell.com
Immunoediting sculpts immunogenicity and thwarts host anti-tumor responses in tumor cells
during tumorigenesis; however, it remains unknown whether metabolic programming of …

[HTML][HTML] Systemic and central nervous system metabolic alterations in Alzheimer's disease

V van der Velpen, T Teav, H Gallart-Ayala… - Alzheimer's Research & …, 2019 - Springer
Background Metabolic alterations, related to cerebral glucose metabolism, brain insulin
resistance, and age-induced mitochondrial dysfunction, play an important role in Alzheimer’s …

Metabolomics analysis identifies different metabotypes of asthma severity

SN Reinke, H Gallart-Ayala, C Gómez… - European …, 2017 - Eur Respiratory Soc
In this study, we sought to determine whether asthma has a metabolic profile and whether
this profile is related to disease severity. We characterised the serum from 22 healthy …