Cells within the synovial tissue may recruit mononuclear phagocytes into the synovial fluid
and tissues of arthritic patients. We investigated the production of the chemotactic cytokine …

… of synovial fibroblast IL-8 was first detected at 4 h for each of the agonists studied. IL-8 levels
steadily increased over the next 20 h to maximum levels at 24 h, with LPS, TNF-a, and IL-1p …

Inflammatory leukocytes play a central role in the pathogenesis of human atherosclerotic
disease, from early atherogenesis to the late stages of atherosclerosis, such as aneurysm …

… to adhere for 8 h. The cells were then washed with PBS and cultured overnight in serum
free media (DMEM with l-glutamine, Pen/Strep). Cells were then stimulated for 24 h in the …

Idiopathic pulmonary fibrosis is characterized by diffuse alveolar damage and severe fibrosis,
resulting in a steady worsening of lung function and gas exchange. Because idiopathic …

The extravasation of leukocytes from the lumen of the vessel to a site of inflammation
requires specific binding events. The interaction of leukocytes with endothelium, via specific …

… expiratory pressure, 2.5–3.0 cm H 2 O) and was ventilated for 5 … a constant pressure of 20
cm H 2 O. Resistance is calculated … The anti-IL-13 or control Ab was administered ip 1 h before …

… At 48 h after CLP, the mortality rate in control mice … h after CLP, causing no statistical
significant difference compared with control (mortality rates in control vs MDC-treated mice at 48 h …

We investigated the role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in
bleomycin-induced lung injury, a model of interstitial lung disease. Bleomycin stimulates a T cell-…

… (▪; 8 mice at 8 h and 10 mice at 24 h) or control serum (□; 8 mice at 8 h and 9 mice at 24 … at
8 h and 10 mice at 24 h) or control serum (□; 8 mice at 8 h and 9 mice at 24 h) 2 h before CLP…