User profiles for H. O. Coxson
Harvey CoxsonPrincipal Scientist - Boehringer Ingelheim Verified email at boehringer-ingelheim.com Cited by 34814 |
An official American Thoracic Society/European Respiratory Society statement: research questions in chronic obstructive pulmonary disease
Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity,
mortality, and resource use worldwide. The goal of this Official American Thoracic Society (…
mortality, and resource use worldwide. The goal of this Official American Thoracic Society (…
Computed tomographic imaging of the airways: relationship to structure and function
Alterations in the structure of the airways, collectively termed airway remodelling, contribute
to airflow obstruction in a variety of chronic lung diseases. While histology has provided …
to airflow obstruction in a variety of chronic lung diseases. While histology has provided …
[HTML][HTML] The nature of small-airway obstruction in chronic obstructive pulmonary disease
…, RM Rogers, FC Sciurba, HO Coxson… - … England Journal of …, 2004 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is a major public health
problem associated with long-term exposure to toxic gases and particles. We examined the …
problem associated with long-term exposure to toxic gases and particles. We examined the …
New and current clinical imaging techniques to study chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized
by both small airway and parenchymal abnormalities. There is increasing evidence to …
by both small airway and parenchymal abnormalities. There is increasing evidence to …
[HTML][HTML] Characterisation of COPD heterogeneity in the ECLIPSE cohort
Background Chronic obstructive pulmonary disease (COPD) is a complex condition with
pulmonary and extra-pulmonary manifestations. This study describes the heterogeneity of …
pulmonary and extra-pulmonary manifestations. This study describes the heterogeneity of …
[HTML][HTML] Small-airway obstruction and emphysema in chronic obstructive pulmonary disease
…, WB Gefter, L Litzky, HO Coxson… - … England Journal of …, 2011 - Mass Medical Soc
Background The major sites of obstruction in chronic obstructive pulmonary disease (COPD)
are small airways (<2 mm in diameter). We wanted to determine whether there was a …
are small airways (<2 mm in diameter). We wanted to determine whether there was a …
[HTML][HTML] Changes in forced expiratory volume in 1 second over time in COPD
Background A key feature of chronic obstructive pulmonary disease (COPD) is an accelerated
rate of decline in forced expiratory volume in 1 second (FEV 1 ), but data on the variability …
rate of decline in forced expiratory volume in 1 second (FEV 1 ), but data on the variability …
[HTML][HTML] Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype
…, C Crim, JC Yates, EK Silverman, HO Coxson… - PloS one, 2012 - journals.plos.org
Background Because chronic obstructive pulmonary disease (COPD) is a heterogeneous
condition, the identification of specific clinical phenotypes is key to developing more effective …
condition, the identification of specific clinical phenotypes is key to developing more effective …
Evaluation of COPD longitudinally to identify predictive surrogate end-points (ECLIPSE)
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and not well
understood. The forced expiratory volume in one second is used for the diagnosis and staging …
understood. The forced expiratory volume in one second is used for the diagnosis and staging …
Amplification of inflammation in emphysema and its association with latent adenoviral infection
…, WM Elliott, B Meshi, HO Coxson… - American journal of …, 2001 - atsjournals.org
This study examines the hypothesis that the cigarette smoke-induced inflammatory process
is amplified in severe emphysema and explores the association of this response with latent …
is amplified in severe emphysema and explores the association of this response with latent …