Few investigators have evaluated the usefulness of the JAK2 V617F mutation for explaining
the phenotypic variations and for predicting the risk of major clinical events in primary …

… of more than 100 g/L and a white blood cell count between 4 × 10 9 /L and 30 × 10 9 /L; a
score of 1 was assigned to either a hemoglobin concentration lower than 100 g/L or a white …

… g per 100 ml. Participant 6, who had β + mutations (IVS I-110/IVS I-6), reached a hemoglobin
level of about 10 g per … independence and a hemoglobin level of 8.4 g per 100 ml at the last …

… Response to the treatment was evaluated by assessing relevant changes in the main
hematologic parameters: an increase in hemoglobin value by more than 2 g/dL or a complete …

Megakaryocytes associate with the bone marrow vasculature where they convert their
cytoplasm into proplatelets that protrude through the vascular endothelium into the lumen and …

BACKGROUND: Extracorporeal photochemotherapy (EPC) has recently been proposed for
the treatment of adults with either acute or chronic GVHD. However, data on children given …

Background: Megakaryocytes release platelets from the tips of cytoplasmic extensions, called
proplatelets. In humans, the regulation of this process is still poorly characterized. Objective…

… Cell debris was precipitated by centrifugation at 4C at 4,000g, and CM was transferred to
a new tube stored at −80C until needed. For the in vitro experiments, we used a 1:1 ratio of …

BACKGROUND: Extracorporeal photochemotherapy (ECP) is a valid therapeutic option in
the treatment of acute and chronic graft‐versus‐host disease (aGVHD and cGVHD, …

Purpose In the WHO diagnostic classification, prefibrotic myelofibrosis (pre-MF) is included
in the category of primary myelofibrosis (PMF). However, strong evidence for this position is …