… (Fig 3, G) cells. For the other significant correlations among bronchial/nasal IL-17–related
cytokines and inflammatory cells see the Online Repository and Figs E6 and E7 at www.…

Severe asthma ( SA ) is associated with neutrophil recruitment and T helper (T H )17
chemokine overexpression in bronchial biopsies. We aimed to evaluate IL ‐17A and IL ‐17F …

Severe asthma might be associated with neutrophil recruitment and Th17 chemokines over-expression
in bronchial biopsies. We studied IL-17-related cytokines in nasal/bronchial …

… Results: Genotyping of rs20541 showed that 26 A/A, 77 A/G and 79 G/G. D min (U) of the
3 genotypes was 1.17±0.300 in A/A, 1.99±0.35 in A/G and 2.85±0.39 in G/G. D min in the 3 …

In severe asthma neutrophil recruitment in bronchial submucosa is associated with steroid
resistance, and in addition Th17-derived cytokines are important in induction and activation of …

IL-17A plays an important role in the pathogenesis of asthma, particularly the neutrophilic
corticosteroid (CS)-resistant subtype of asthma. Clinical studies suggest that a subset of …

Asthma is characterized by multiple immunological mechanisms (endotypes) determining
variable clinical presentations (phenotypes). The identification of endotypic mechanisms is …

Host immune responses at the site of Mycobacterium tuberculosis infection can mediate
pathogenesis of tuberculosis (TB) and onward transmission of infection. We hypothesized that …

Tryptophan metabolic pathway is involved in pathogenic mechanisms of asthma. This study
aimed to evaluate tryptophan metabolites and neopterin in a group of asthmatic children. …

Background Transcriptomic changes in patients who respond clinically to biological therapies
may identify responses in other tissues or diseases. Objective We sought to determine …