Long‐term expanding human airway organoids for disease modeling

…, E Cuppen, A van Oudenaarden, FE Coenjaerts… - The EMBO …, 2019 - embopress.org
Organoids are self‐organizing 3D structures grown from stem cells that recapitulate essential
aspects of organ structure and function. Here, we describe a method to establish long‐term…

Progressive multifocal leukoencephalopathy in patients treated with fumaric acid esters: a review of 19 cases

…, BW van Oosten, DJ Nieuwkamp, FE Coenjaerts… - Journal of …, 2017 - Springer
Progressive multifocal leukoencephalopathy (PML) is a rare and potentially fatal condition
caused by a brain infection with JC polyomavirus (JCV). PML develops almost exclusively in …

Effects of the capsular polysaccharides of cryptococcus neoformans on phagocyte migration and inflammatory mediators [general articles]

…, AIM Hoepelman, FEJ Coenjaerts - Current medicinal …, 2004 - ingentaconnect.com
An important virulence factor of the pathogenic fungus Cryptococcus neoformans is its
polysaccharide capsule. The capsular polysaccharides glucuronoxylomannan (GXM), …

Disease severity and viral load are correlated in infants with primary respiratory syncytial virus infection in the community

ML Houben, FEJ Coenjaerts… - Journal of medical …, 2010 - Wiley Online Library
Respiratory syncytial virus (RSV) is a major cause of respiratory tract infections in infants,
with remarkable variability in disease severity. Factors determining severity of disease in …

[HTML][HTML] Aetiology of lower respiratory tract infection in adults in primary care: a prospective study in 11 European countries

…, S Coenen, K Loens, C Lammens, F Coenjaerts… - Clinical microbiology …, 2018 - Elsevier
Objectives To describe the role of bacteria (including bacterial resistance), viruses (including
those recently described) and mixed bacterial–viral infections in adults presenting to …

The role of Toll-like receptors in regulating the immune response against respiratory syncytial virus

…, GM van Bleek, F Coenjaerts - Critical Reviews™ in …, 2009 - dl.begellhouse.com
… Upon challenge with UVinactivated whole RSV or RSV-F, monocytes respond with an
increased production of IL-6, IL-8, TNF-α, and IL-1β,48 which is similar to the cytokine expression …

Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion

…, T Dudez, MJA Van Kempen, FEJ Coenjaerts… - Circulation, 2010 - Am Heart Assoc
… ) and VCAM-1 (D through F). Sections were counterstained with Evans blue (red) and DAPI
(blue). n=5. … Bar=200 μm for A through C; 100 μm for D through F; and 50 μm for G through I. …

Respiratory syncytial virus-induced activation and migration of respiratory dendritic cells and subsequent antigen presentation in the lung-draining lymph node

MV Lukens, D Kruijsen, FEJ Coenjaerts… - Journal of …, 2009 - Am Soc Microbiol
In the respiratory tract, different dendritic cell (DC) populations guard a tight balance
between tolerance and immunity to infectious or harmless materials to which the airways are …

A Systemic Neutrophil Response Precedes Robust CD8+ T-Cell Activation during Natural Respiratory Syncytial Virus Infection in Infants

MV Lukens, AC van de Pol, FEJ Coenjaerts… - Journal of …, 2010 - Am Soc Microbiol
Severe primary respiratory syncytial virus (RSV) infections are characterized by bronchiolitis
accompanied by wheezing. Controversy exists as to whether infants suffer from virus-…

[HTML][HTML] Detection of multiple respiratory pathogens during primary respiratory infection: nasal swab versus nasopharyngeal aspirate using real-time polymerase chain …

TJ Meerhoff, ML Houben, FEJ Coenjaerts… - European journal of …, 2010 - Springer
In this study, we present the multiple detection of respiratory viruses in infants during primary
respiratory illness, investigate the sensitivity of nasal swabs and nasopharyngeal aspirates, …