User profiles for F. Blackhall

F Blackhall

University of Manchester
Verified email at christie.nhs.uk
Cited by 38111

Molecular analysis of circulating tumour cells—biology and biomarkers

…, RL Metcalf, L Carter, G Brady, FH Blackhall… - Nature reviews Clinical …, 2014 - nature.com
Growing evidence for intratumour heterogeneity informs us that single-site biopsies fall short
of revealing the complete genomic landscape of a tumour. With an expanding repertoire of …

Treatment of unexplained chronic cough: CHEST guideline and expert panel report

…, SS Birring, TM Adams, AF Barker, F Blackhall… - Chest, 2016 - Elsevier
Background Unexplained chronic cough (UCC) causes significant impairments in quality of
life. Effective assessment and treatment approaches are needed for UCC. Methods This …

Anatomy and neurophysiology of cough: CHEST Guideline and Expert Panel report

…, KW Altman, AF Barker, SS Birring, F Blackhall… - Chest, 2014 - Elsevier
Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated
sensory nerves play essential roles in regulating cough. These vagal sensory nerves …

[HTML][HTML] First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer

…, KD Wilner, J Tursi, F Blackhall - … England Journal of …, 2014 - Mass Medical Soc
Background The efficacy of the ALK inhibitor crizotinib as compared with standard
chemotherapy as first-line treatment for advanced ALK-positive non–small-cell lung cancer (NSCLC) …

[HTML][HTML] Tracking the evolution of non–small-cell lung cancer

…, R Thakrar, A Ahmed, F Blackhall… - … England Journal of …, 2017 - Mass Medical Soc
Background Among patients with non–small-cell lung cancer (NSCLC), data on intratumor
heterogeneity and cancer genome evolution have been limited to small retrospective cohorts. …

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

…, SM Janes, R Thakrar, A Ahmed, F Blackhall… - Nature, 2017 - nature.com
The early detection of relapse following primary surgery for non-small-cell lung cancer and
the characterization of emerging subclones, which seed metastatic sites, might offer new …

[HTML][HTML] Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer

…, B Besse, BJ Solomon, F Blackhall… - … England Journal of …, 2013 - Mass Medical Soc
Background In single-group studies, chromosomal rearrangements of the anaplastic lymphoma
kinase gene (ALK) have been associated with marked clinical responses to crizotinib, an …

[PDF][PDF] Allele-specific HLA loss and immune escape in lung cancer evolution

…, K Moore, R Waddington, J Novasio, F Blackhall… - Cell, 2017 - cell.com
… (E and F) Phylogenetic trees for each lung adenocarcinoma (E) and lung squamous cell
carcinomas (F) showing evidence of HLA LOH have been annotated with the most likely timing …

[PDF][PDF] Evaluation and prognostic significance of circulating tumor cells in patients with non–small-cell lung cancer

…, G Clack, M Ranson, C Dive, FH Blackhall - Journal of clinical …, 2011 - researchgate.net
Purpose Lung cancer is the leading cause of cancer-related death worldwide. Non–small-cell
lung cancer (NSCLC) lacks validated biomarkers to predict treatment response. This study …

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer

…, L Priest, L Carter, C Tate, CJ Miller, F Blackhall… - Nature medicine, 2014 - nature.com
Small-cell lung cancer (SCLC), an aggressive neuroendocrine tumor with early dissemination
and dismal prognosis, accounts for 15–20% of lung cancer cases and ∼200,000 deaths …