User profiles for E. Koay

Eugene Koay

MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 9457

[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges

AD Singhi, EJ Koay, ST Chari, A Maitra - Gastroenterology, 2019 - Elsevier
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable and …

Early detection of pancreatic cancer

…, D Li, W Greenhalf, CY Jeon, EJ Koay… - The lancet …, 2020 - thelancet.com
… We review early detection biomarkers, explore the potential of using social media for detection,
appraise prediction models developed using electronic health records and research data…

Cancer overdiagnosis: a biological challenge and clinical dilemma

S Srivastava, EJ Koay, AD Borowsky… - Nature Reviews …, 2019 - nature.com
For cancer screening to be successful, it should primarily detect cancers with lethal potential
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …

Prevalence of primary aldosteronism among Asian hypertensive patients in Singapore

KC Loh, ES Koay, MC Khaw… - The Journal of …, 2000 - academic.oup.com
Recent studies using the ratio of plasma aldosterone concentration (PAC) to PRA as the
screening test for primary aldosteronism in hypertensive populations suggested that the …

An injectable nanoparticle generator enhances delivery of cancer therapeutics

…, E Koay, Y Huang, J Liu, JE Ensor, E Blanco… - Nature …, 2016 - nature.com
The efficacy of cancer drugs is often limited because only a small fraction of the administered
dose accumulates in tumors. Here we report an injectable nanoparticle generator (iNPG) …

[HTML][HTML] Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer

…, LK Tai, LL Wong, LL Chiu, SK Sethi, ESC Koay - Molecular & Cellular …, 2005 - ASBMB
The receptor tyrosine kinase ErbB2 (HER-2/neu) is overexpressed in up to 30% of breast
cancers and is associated with poor prognosis and an increased likelihood of metastasis …

Real-Time PCR for Detection and Identification of Plasmodium spp

KA Mangold, RU Manson, ESC Koay… - Journal of clinical …, 2005 - Am Soc Microbiol
Rapid and accurate detection of malaria parasites in blood is needed to institute proper
therapy. We developed and used a real-time PCR assay to detect and distinguish four …

Nanoplasmonic quantification of tumour-derived extracellular vesicles in plasma microsamples for diagnosis and treatment monitoring

…, DW Bernard, Y Li, K Yokoi, MH Katz, EJ Koay… - Nature biomedical …, 2017 - nature.com
… b–e, ROC curves of the ability of plasma EphA2-EV (black) and CA19-9 (red) levels to … (d)
and stage I/II pancreatic cancer from pancreatitis cases (e). ROC area under the curve (AUC) …

Circulating nucleic acids are associated with outcomes of patients with pancreatic cancer

…, PA Guerrero, N Kamyabi, J Zhao, MW Hurd, EJ Koay… - Gastroenterology, 2019 - Elsevier
… After confirming the proportional hazards assumption using Schoenfeld residuals, the Cox
proportional hazards model was used to obtain hazard ratios (e^∖beta) and P values in both …

[HTML][HTML] Ablative radiotherapy doses lead to a substantial prolongation of survival in patients with inoperable intrahepatic cholangiocarcinoma: a retrospective dose …

…, AJ Bishop, CW Swanick, EJ Koay… - Journal of Clinical …, 2016 - ncbi.nlm.nih.gov
Purpose Standard therapies for localized inoperable intrahepatic cholangiocarcinoma (IHCC)
are ineffective. Advances in radiotherapy (RT) techniques and image guidance have …