The incidence of hypersensitivity pneumonitis (HP) is lower in smokers than in nonsmokers.
Because nicotine is immunosuppressive, we hypothesized that it could have a protective …

… and BAL fluids of normal and asymptomatic subjects efficiently suppress Th-cell activation,
while those from blood and … an exacerbated immune response and clinically significant lung …

Exposure to swine confinement buildings has a negative impact on respiratory health. A
short exposure to this environment results in an acute airway inflammatory response. The …

Hypersensitivity pneumonitis (HP), a lung disease with “flulike” symptoms, results from
repeated exposures to well defined, nonpathogenic antigens. This study examined whether …

… by significantly fewer inflammatory cells in the bronchoalveolar lavage and in lung tissue
and reduced SR-specific serum and bronchoalveolar lavage Ig levels. Production of IL-4, IL-10, …

This study investigated whether clean swine confinement buildings (SCB) are less harmful
to the respiratory system than older and dirtier facilities. Eight healthy volunteers were …

… and cigarette smoking. The aims of the study were to compare the expression of CD80 and
… exposed subjects, normal nonsmoking subjects, and smokers, and to assess the effect of an …

… and CT but they all had a lymphocytic alveolitis (30, 34, and 68… functions, CT, and percentage
of BAL lymphocytes (3 and 13%)… that can lead to HP and documented a protective effect of …

Nicotinic agonists, including 1,1-dimethyl-4-phenylpiperazinium (DMPP), have anti-inflammatory
properties and in some instances smooth muscle relaxing effects. Since inflammation …

… , we and others demonstrated that animals instilled with live viruses developed, as expected,
a transient lung inflammation that peaked between 4 and 10 days after the instillation and …