Outcomes for COPD pharmacological trials: from lung function to biomarkers

…, SD Sullivan, JA Wedzicha, EF Wouters - European respiratory …, 2008 - Eur Respiratory Soc
The American Thoracic Society/European Respiratory Society jointly created a Task Force
on “Outcomes for COPD pharmacological trials: from lung function to biomarkers” to inform …

Usefulness of lactate dehydrogenase and its isoenzymes as indicators of lung damage or inflammation

…, RF Henderson, EF Wouters… - European …, 1996 - Eur Respiratory Soc
This review describes the usefulness of monitoring the activity level of lactate dehydrogenase
(LDH) and its isoenzyme pattern as indicators of pathological conditions in the lungs, such …

The versatile use of exhaled volatile organic compounds in human health and disease

…, JW Dallinga, A Smolinska, EF Wouters… - Journal of breath …, 2012 - iopscience.iop.org
Exhaled breath contains thousands of volatile organic compounds (VOCs) of which the
composition varies depending on health status. Various metabolic processes within the body …

[HTML][HTML] Body composition and mortality in chronic obstructive pulmonary disease

…, CA Weling-Scheepers, EF Wouters - The American journal of …, 2005 - Elsevier
Background: Survival studies have consistently shown significantly greater mortality rates in
underweight and normal-weight patients with chronic obstructive pulmonary disease (COPD…

Evidence for a relation between metabolic derangements and increased levels of inflammatory mediators in a subgroup of patients with chronic obstructive pulmonary …

…, AJS Van den Brekel, MA Dentener, EF Wouters - Thorax, 1996 - thorax.bmj.com
BACKGROUND: An increase in resting energy expenditure (REE) commonly occurs in
patients with chronic obstructive pulmonary disease (COPD), the cause of which is as yet …

Physiologic effects of nutritional support and anabolic steroids in patients with chronic obstructive pulmonary disease. A placebo-controlled randomized trial.

…, ROB Mostert, RJ Pluymers, EF Wouters - American journal of …, 1995 - atsjournals.org
Nutritional depletion commonly occurs in patients with COPD, causing muscle wasting and
impaired physiologic function. Two hundred seventeen patients with COPD participated in a …

Local and systemic inflammation in patients with chronic obstructive pulmonary disease: soluble tumor necrosis factor receptors are increased in sputum

…, WA Buurman, MA Dentener, EF Wouters - American journal of …, 2002 - atsjournals.org
… Schols AM, Buurman WA, Staal van den Brekel AJ, Dentener MA, Wouters EF. Evidence for
a relation between metabolic derangements and increased levels of inflammatory mediators …

Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD

…, WC Baken, GJ Wesseling, EF Wouters - European …, 1994 - Eur Respiratory Soc
Although increasing attention has been paid to nutritional aspects in chronic obstructive
pulmonary disease (COPD), limited information is available regarding the prevalence and …

The impact of aging and smoking on the future burden of chronic obstructive pulmonary disease: a model analysis in the Netherlands

…, RT Hoogenveen, EF WOUTERS… - American journal of …, 2001 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) causes extensive disability, primarily among
the elderly. On the World Health Organization ranking list of disability-adjusted life years (…

Peak exercise response in relation to tissue depletion in patients with chronic obstructive pulmonary disease

…, AM Schols, R Mostert, EF Wouters - European Respiratory …, 1997 - Eur Respiratory Soc
In several studies a correlation between body weight and peak exercise capacity has been
found in patients with chronic obstructive pulmonary disease (COPD). In the present study a …