User profiles for D. Sharkey

David Sharkey, PhD

- Verified email at adelaide.edu.au - Cited by 2797

don sharkey

- Verified email at nottingham.ac.uk - Cited by 1884

Transforming growth factor β—a mediator of immune deviation in seminal plasma

…, WV Ingman, S O'Leary, DJ Sharkey… - Journal of reproductive …, 2002 - Elsevier
TGFβ is a potent immune deviating agent, driving active forms of immune tolerance in peripheral
tissues through effects on the induction and resolution of inflammatory responses and …

[HTML][HTML] Seminal fluid and fertility in women

SA Robertson, DJ Sharkey - Fertility and sterility, 2016 - Elsevier
… washed sperm, and seminal plasma with different patterns of cytokine release, suggesting
that both the plasma fraction and sperm contribute to the in vivo response in women (Sharkey

Seminal fluid and the generation of regulatory T cells for embryo implantation

SA Robertson, JR Prins, DJ Sharkey… - American journal of …, 2013 - Wiley Online Library
T regulatory (Treg) cells are essential mediators of the maternal immune adaptation necessary
for embryo implantation. In mice, insufficient Treg cell activity results in implantation failure…

Identification and characterization of podocalyxin--the major sialoprotein of the renal glomerular epithelial cell.

D Kerjaschki, DJ Sharkey, MG Farquhar - The Journal of cell biology, 1984 - rupress.org
The glomerular epithelial polyanion is a specialized cell surface component found on renal
glomerular epithelial cells (podocytes) that is rich in sialoprotein(s), as detected by staining …

[HTML][HTML] Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance

…, S Ladhani, ES Draper, D Sharkey… - The Lancet Child & …, 2021 - thelancet.com
Background Babies differ from older children with regard to their exposure to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). However, data describing the effect of …

Seminal fluid induces leukocyte recruitment and cytokine and chemokine mRNA expression in the human cervix after coitus

DJ Sharkey, KP Tremellen, MJ Jasper… - The Journal of …, 2012 - journals.aai.org
… All couples totally abstained from penetrative intercourse for 2 d before the first biopsy,
and condoms were used for 5 d before this to ensure that no sperm would be present in the …

Seminal plasma differentially regulates inflammatory cytokine gene expression in human cervical and vaginal epithelial cells

DJ Sharkey, AM Macpherson… - Molecular human …, 2007 - academic.oup.com
Exposure to semen elicits an inflammatory response in the female reproductive tract of rodents
and other animals. The nature and regulation of any similar response in humans is poorly …

TGF-β mediates proinflammatory seminal fluid signaling in human cervical epithelial cells

DJ Sharkey, AM Macpherson, KP Tremellen… - The Journal of …, 2012 - journals.aai.org
… Cervical epithelial cells were allowed to attach and displace the 3T3 fibroblasts for 5–7 d,
when unattached epithelial cells and 3T3 cells were aspirated and media was replaced with …

Phylogenetics of the brachyuran crabs (Crustacea: Decapoda): the status of Podotremata based on small subunit nuclear ribosomal RNA

ST Ahyong, JCY Lai, D Sharkey, DJ Colgan… - Molecular Phylogenetics …, 2007 - Elsevier
The true crabs, the Brachyura, are generally divided into two major groups: Eubrachyura or ‘advanced’
crabs, and Podotremata or ‘primitive’ crabs. The status of Podotremata is one of …

[HTML][HTML] Adipose tissue and fetal programming

ME Symonds, M Pope, D Sharkey, H Budge - Diabetologia, 2012 - Springer
Adipose tissue function changes with development. In the newborn, brown adipose tissue (BAT)
is essential for ensuring effective adaptation to the extrauterine environment, and its …