Respiratory microbiota: addressing clinical questions, informing clinical practice

GB Rogers, D Shaw, RL Marsh, MP Carroll, DJ Serisier… - Thorax, 2015 - thorax.bmj.com
Over the last decade, technological advances have revolutionised efforts to understand the
role played by microbes in airways disease. With the application of ever more sophisticated …

Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non–cystic fibrosis bronchiectasis: the BLESS randomized controlled trial

DJ Serisier, ML Martin, MA McGuckin, R Lourie… - Jama, 2013 - jamanetwork.com
Importance Macrolide antibiotics such as erythromycin may improve clinical outcomes in
non–cystic fibrosis (CF) bronchiectasis, although associated risks of macrolide resistance are …

Characterization of bacterial community diversity in cystic fibrosis lung infections by use of 16S ribosomal DNA terminal restriction fragment length polymorphism …

GB Rogers, MP Carroll, DJ Serisier… - Journal of clinical …, 2004 - Am Soc Microbiol
Progressive loss of lung function resulting from the inflammatory response to bacterial
colonization is the leading cause of mortality in cystic fibrosis (CF) patients. A greater …

Inhaled, dual release liposomal ciprofloxacin in non-cystic fibrosis bronchiectasis (ORBIT-2): a randomised, double-blind, placebo-controlled trial

DJ Serisier, D Bilton, A De Soyza, PJ Thompson… - Thorax, 2013 - thorax.bmj.com
… David J Serisier1, … Correspondence to Dr David J Serisier, Department of Respiratory
Medicine, Level 9 Mater Adult Hospital, Raymond Tce, South Brisbane, QLD 4101, … Serisier DJ …

Clopidogrel plus aspirin versus warfarin in patients with stroke and aortic arch plaques

…, D Saudeau, P Michel, S D'Ombrogio, D Serisier… - Stroke, 2014 - Am Heart Assoc
Background and Purpose— Severe atherosclerosis in the aortic arch is associated with a
high risk of recurrent vascular events, but the optimal antithrombotic strategy is unclear. …

A novel microbiota stratification system predicts future exacerbations in bronchiectasis

…, DW Rivett, MA McGuckin, DJ Serisier - Annals of the …, 2014 - atsjournals.org
Rationale: Although airway microbiota composition correlates with clinical measures in non–cystic
fibrosis bronchiectasis, these data are unlikely to provide useful prognostic …

Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition

…, SK Thomson, KD Bruce, ML Martin, DJ Serisier - Thorax, 2013 - thorax.bmj.com
Rationale Despite the potentially important roles for infection in adult non-cystic fibrosis (CF)
bronchiectasis disease progression, the bacterial species present in the lower airways of …

The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind …

…, KD Bruce, ML Martin, LD Burr, DJ Serisier - The lancet Respiratory …, 2014 - thelancet.com
Background Long-term macrolide treatment has proven benefit in inflammatory airways
diseases, but whether it leads to changes in the composition of respiratory microbiota is unknown…

Risks of population antimicrobial resistance associated with chronic macrolide use for inflammatory airway diseases

DJ Serisier - The Lancet Respiratory Medicine, 2013 - thelancet.com
Macrolide antibiotics have established efficacy in the management of cystic fibrosis and diffuse
panbronchiolitis—uncommon lung diseases with substantial morbidity and the potential …

Use of 16S rRNA gene profiling by terminal restriction fragment length polymorphism analysis to compare bacterial communities in sputum and mouthwash samples …

GB Rogers, MP Carroll, DJ Serisier… - Journal of clinical …, 2006 - Am Soc Microbiol
The bacterial communities present in the oral cavity and the lungs of 19 adult cystic fibrosis (CF)
patients were compared by using terminal restriction fragment length polymorphism …