… McDaniel LS and Briles DE Monoclonal antibodies against surface components of Streptococcus
pneumoniae Monoclonal antibodies against bacteria. Macario AJL and de Macario EC …

… Author links open overlay panel David E Briles a b , Susan K Hollingshead a , Gary S …
better protection, however, than either protein by itself (Briles et al., manuscript in preparation). …

Streptococcus pneumoniae is a Gram-Positive pathogen that is a major causative agent of
pneumonia, otitis media, sepsis and meningitis across the world. The World Health …

… Naturally occurring anti-PC antibodies are commonly found in sera of mouse strains (35)
other than CBA/N and are easily demonstrable in normal human sera (DE Briles and C. Forman…

Insertion-duplication mutagenesis was used to construct a pneumolysin-negative derivative
of Streptococcus pneumoniae. This was achieved by first transforming the nonencapsulated …

… Production of IgG1 and IgG2a anti-D-alanine antibodies by x-irradiated mice repopulated
with … A critical study of the IgG subclasses of Rh anti-D antibodies formed in pregnancy and in …

Pneumococcal surface protein A (PspA) is a surface-exposed protein virulence factor for
Streptococcus pneumoniae. In this study, no significant depletion of serum complement was …

… recent clinical isolates of pneumococci of all capsular serotypes, a finding which argues that
they are not recent acquisitions from another streptococcal species (Hollingshead and Briles…

… Yother and DE Briles, unpublished data), and none of the monoclonal antibodies reacted
with components of the mutant bacterial lysate. Each monoclonal antibody, however, detected …

In the mouse, most anti-PC antibody is found in one of the three murine anti-PC idiotype
families: T15, M603, or M511. The antibodies within each of these idiotypic families have …