User profiles for D. Briles
David BrilesProfessor University of Alabama at Birmingham Verified email at uab.edu Cited by 26669 |
Pneumococcal diversity: considerations for new vaccine strategies with emphasis on pneumococcal surface protein A (PspA)
DE Briles, RC Tart, E Swiatlo, JP Dillard… - Clinical microbiology …, 1998 - Am Soc Microbiol
… McDaniel LS and Briles DE Monoclonal antibodies against surface components of Streptococcus
pneumoniae Monoclonal antibodies against bacteria. Macario AJL and de Macario EC …
pneumoniae Monoclonal antibodies against bacteria. Macario AJL and de Macario EC …
The potential for using protein vaccines to protect against otitis media caused by Streptococcus pneumoniae
… Author links open overlay panel David E Briles a b , Susan K Hollingshead a , Gary S …
better protection, however, than either protein by itself (Briles et al., manuscript in preparation). …
better protection, however, than either protein by itself (Briles et al., manuscript in preparation). …
Pneumococcal vaccines
Streptococcus pneumoniae is a Gram-Positive pathogen that is a major causative agent of
pneumonia, otitis media, sepsis and meningitis across the world. The World Health …
pneumonia, otitis media, sepsis and meningitis across the world. The World Health …
Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 streptococcus pneumoniae.
DE Briles, M Nahm, K Schroer, J Davie… - The Journal of …, 1981 - rupress.org
… Naturally occurring anti-PC antibodies are commonly found in sera of mouse strains (35)
other than CBA/N and are easily demonstrable in normal human sera (DE Briles and C. Forman…
other than CBA/N and are easily demonstrable in normal human sera (DE Briles and C. Forman…
Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae
AM Berry, J Yother, DE Briles, D Hansman… - Infection and …, 1989 - Am Soc Microbiol
Insertion-duplication mutagenesis was used to construct a pneumolysin-negative derivative
of Streptococcus pneumoniae. This was achieved by first transforming the nonencapsulated …
of Streptococcus pneumoniae. This was achieved by first transforming the nonencapsulated …
Subclass restriction of murine anti-carbohydrate antibodies
RM Perlmutter, D Hansburg, DE Briles… - The Journal of …, 1978 - journals.aai.org
… Production of IgG1 and IgG2a anti-D-alanine antibodies by x-irradiated mice repopulated
with … A critical study of the IgG subclasses of Rh anti-D antibodies formed in pregnancy and in …
with … A critical study of the IgG subclasses of Rh anti-D antibodies formed in pregnancy and in …
Pneumococcal Surface Protein A Inhibits Complement Activation by Streptococcus pneumoniae
AHT Tu, RL Fulgham, MA McCrory, DE Briles… - Infection and …, 1999 - Am Soc Microbiol
Pneumococcal surface protein A (PspA) is a surface-exposed protein virulence factor for
Streptococcus pneumoniae. In this study, no significant depletion of serum complement was …
Streptococcus pneumoniae. In this study, no significant depletion of serum complement was …
Diversity of PspA: Mosaic Genes and Evidence for Past Recombination in Streptococcus pneumoniae
SK Hollingshead, R Becker, DE Briles - Infection and immunity, 2000 - Am Soc Microbiol
… recent clinical isolates of pneumococci of all capsular serotypes, a finding which argues that
they are not recent acquisitions from another streptococcal species (Hollingshead and Briles…
they are not recent acquisitions from another streptococcal species (Hollingshead and Briles…
Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae
…, LS McDaniel, BM Gray, DE Briles - Infection and …, 1990 - Am Soc Microbiol
… Yother and DE Briles, unpublished data), and none of the monoclonal antibodies reacted
with components of the mutant bacterial lysate. Each monoclonal antibody, however, detected …
with components of the mutant bacterial lysate. Each monoclonal antibody, however, detected …
Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.
DE Briles, C Forman, S Hudak, JL Claflin - The Journal of experimental …, 1982 - rupress.org
In the mouse, most anti-PC antibody is found in one of the three murine anti-PC idiotype
families: T15, M603, or M511. The antibodies within each of these idiotypic families have …
families: T15, M603, or M511. The antibodies within each of these idiotypic families have …