Prevention of preterm birth: harnessing science to address the global epidemic

…, L Muglia, MG Gravett, E Lackritz, C Gravett - Science translational …, 2014 - science.org
… Essential components of this crosstalk include killer cell immunoglobin-like receptor (KIR)
haplotype A (AA alleles) and fetal human leukocyte antigen–C (HLA-C) genotype. Interaction …

[HTML][HTML] Cysteinyl leukotriene receptor-1 antagonists as modulators of innate immune cell function

…, CM Gravett, R Anderson, C Feldman - Journal of immunology …, 2014 - hindawi.com
Cysteinyl leukotrienes (cysLTs) are produced predominantly by cells of the innate immune
system, especially basophils, eosinophils, mast cells, and monocytes/macrophages. …

M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion

…, HS Sekhon, A Lu, J Arredondo, D Sauer, C Gravett… - Cancer research, 2007 - AACR
… ), and M3 mAChR (Research and Diagnostic Antibodies, North Las Vegas, NV) were diluted
by 1,000- to 2,000-fold in the blocking buffer and incubated overnight with membranes at 4C

Activated cholinergic signaling provides a target in squamous cell lung carcinoma

…, XW Fu, M Maier, Y Jia, J Duan, BJ Proskosil, C Gravett… - Cancer research, 2008 - AACR
… Supernatant (1 mL) was lyophilized and stored at −80C. The dried samples were dissolved
in 80 to 120 μL of the HPLC mobile phase and filtered and 10 μL were injected into the HPLC…

Montelukast inhibits neutrophil pro‐inflammatory activity by a cyclic AMP‐dependent mechanism

R Anderson, AJ Theron, CM Gravett… - British journal of …, 2009 - Wiley Online Library
Background and purpose: The objective of this study was to characterize the effects of the
cysteinyl leukotriene receptor antagonist, montelukast (0.1–2 µmol·L −1 ), on Ca 2+ ‐…

[HTML][HTML] Non-reassuring fetal status: case definition & guidelines for data collection, analysis, and presentation of immunization safety data

C Gravett, LO Eckert, MG Gravett, DJ Dudley… - Vaccine, 2016 - ncbi.nlm.nih.gov
Non-reassuring fetal status is a term used to describe suspected fetal hypoxia and is meant
to replace the more ubiquitous term “fetal distress.” Fetal distress, defined as progressive …

[HTML][HTML] Serious and life-threatening pregnancy-related infections: opportunities to reduce the global burden

CA Gravett, MG Gravett, ET Martin, JD Bernson, S Khan… - 2012 - journals.plos.org
… gonorrhoeae and C. trachomatis may also cause PPE [11]. Cesarean section is an
important risk factor for PPE. … gonorrhoeae and C. trachomatis, are an important cause of …

[HTML][HTML] Epidemiology and aetiology of maternal parasitic infections in low-and middle-income countries

T Roberts, CA Gravett, PP Velu… - Journal of global …, 2011 - ncbi.nlm.nih.gov
Background There have been very few systematic reviews looking at maternal infections in
the developing world, even though cutting maternal mortality by three quarters is United …

Elevated second trimester maternal serum β‐HCG concentrations and subsequent adverse pregnancy outcome

CP Gravett, JG Buckmaster, PT Watson… - American journal of …, 1992 - Wiley Online Library
Previous studies have found an association between elevated second trimester maternal
serum α‐fetoprotein (MS‐AFP), in the absence of fetal anomalies, and adverse pregnancy …

[HTML][HTML] Emerging biomarkers for the diagnosis of severe neonatal infections applicable to low resource settings

TA Wagner, CA Gravett, S Healy, V Soma… - Journal of global …, 2011 - ncbi.nlm.nih.gov
More than 500 000 children die each year in low resource settings due to serious neonatal
infections. Better diagnostics that can be utilized in these settings to identify infected infants …