Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis

…, L Berry, C Salama, IO Rosas, B Ruiz-Antorán… - Jama, 2021 - jamanetwork.com
Importance Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized
for COVID-19 have variously reported benefit, no effect, and harm. Objective To estimate the …

Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort

JL Calleja, J Crespo, D Rincón, B Ruiz-Antorán… - Journal of …, 2017 - Elsevier
Background & Aims Clinical trials evaluating second-generation direct-acting antiviral agents
(DAAs) have shown excellent rates of sustained virologic response (SVR) and good safety …

A retrospective controlled cohort study of the impact of glucocorticoid treatment in SARS-CoV-2 infection mortality

A Fernández-Cruz, B Ruiz-Antorán… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Evidence to support the use of steroids in coronavirus disease 2019 (COVID-19) pneumonia
is lacking. We aim to determine the impact of steroid use for COVID-19 pneumonia on …

[HTML][HTML] Combination of tocilizumab and steroids to improve mortality in patients with severe COVID-19 infection: a Spanish, multicenter, cohort study

B Ruiz-Antorán, A Sancho-López, F Torres… - Infectious diseases and …, 2021 - Springer
Background We aimed to determine the impact of tocilizumab use on severe COVID-19 (coronavirus
disease 19) pneumonia mortality. Methods We performed a multicentre …

[HTML][HTML] Efficacy and safety of sarilumab in patients with COVID19 pneumonia: a randomized, phase III clinical trial (SARTRE study)

…, AF Caballero-Bermejo, B Ruiz-Antorán… - Infectious diseases and …, 2021 - Springer
Introduction SARS-CoV-2 pneumonia is often associated with hyper-inflammation. The
cytokine-storm-like is one of the targets of current therapies for coronavirus disease 2019 (COVID-…

Cervical pessary compared with vaginal progesterone for preventing early preterm birth: a randomized controlled trial

…, B Ruiz-Antorán, B Adiego-Burgos… - Obstetrics & …, 2018 - journals.lww.com
OBJECTIVE: To compare the effectiveness of a cervical pessary and vaginal progesterone to
prevent spontaneous preterm births in pregnant women with cervical lengths 25 mm or less …

Real-world effectiveness and safety of oral combination antiviral therapy for hepatitis C virus genotype 4 infection

…, I Fernández, B Sacristan, B Ruiz-Antorán… - Clinical …, 2017 - Elsevier
Patients with hepatitis C virus (HCV) genotype 4 infection are poorly represented in clinical
trials of second-generation direct-acting antiviral agents (DAAs). More data are needed to …

[HTML][HTML] Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol …

AF Caballero Bermejo, B Ruiz-Antorán… - Trials, 2020 - Springer
Objectives In some patients, acute, life-threatening respiratory injury produced by viruses such
as SARS-CoV and other viral pneumonia are associated with an over-exuberant cytokine …

Use of non-specific intravenous human immunoglobulins in Spanish hospitals; need for a hospital protocol

B Ruiz-Antorán, A Agustí Escasany… - European journal of …, 2010 - Springer
Intravenous immunoglobulin (IVIG) use in non-approved indications, the increase in consumption
and its high cost recommend rationalisation in its utilisation. Aims To assess the use of …

The right time for steroids in COVID-19

A Fernández-Cruz, B Ruiz-Antorán… - Clinical Infectious …, 2021 - academic.oup.com
To the Editor—We have read with interest the work by Fadel et al [1] who describe a beneficial
effect of early steroid treatment in patients with moderate to severe coronavirus disease …