Clinical translation of FLASH radiotherapy: Why and how?

…, P Montay-Gruel, PG Jorge, C Bailat, B Petit… - Radiotherapy and …, 2019 - Elsevier
Over the past decades, technological advances have transformed radiation therapy (RT)
into a precise and powerful treatment for cancer patients. Nevertheless, the treatment of …

[HTML][HTML] L-asparaginase-based treatment of 15 western patients with extranodal NK/T-cell lymphoma and leukemia and a review of the literature

A Jaccard, B Petit, S Girault, F Suarez, R Gressin… - Annals of oncology, 2009 - Elsevier
… It is characterized by a CD3ε phenotype, with no surface CD3 or T-cell receptor expression,
an activated cytotoxic profile with perforin and granzyme B expression, and common …

Interval training at VO2max: effects on aerobic performance and overtraining markers.

VL Billat, B Flechet, B Petit, G Muriaux… - Medicine and science …, 1999 - europepmc.org
Purpose Between inefficient training and overtraining, an appropriate training stimulus (in
terms of intensity and duration) has to be determined in accordance with individual capacities. …

The advantage of FLASH radiotherapy confirmed in mini-pig and cat-cancer patients

…, V Favaudon, M Jaccard, JF Germond, B Petit… - Clinical Cancer …, 2019 - AACR
… be limited to depilation, which occurred 3 weeks later for the skin patches exposed to FLASH-RT
and was transient (lasting only 4 weeks) for doses ≤ 31 Gy FLASH-RT (Table 1A and B)…

Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species

…, BD Allen, J Ollivier, B Petit… - Proceedings of the …, 2019 - National Acad Sciences
Here, we highlight the potential translational benefits of delivering FLASH radiotherapy using
ultra-high dose rates (>100 Gy⋅s −1 ). Compared with conventional dose-rate (CONV; 0.07…

Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a …

…, L Ysebaert, A Devidas, B Petit… - Blood, The Journal …, 2011 - ashpublications.org
Extranodal NK/T-cell lymphoma, nasal type, is a rare and highly aggressive disease with a
grim prognosis. No therapeutic strategy is currently identified in relapsing patients. We report …

Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

…, M Jaccard, G Boivin, JF Germond, B Petit… - Radiotherapy and …, 2017 - Elsevier
This study shows for the first time that normal brain tissue toxicities after WBI can be reduced
with increased dose rate. Spatial memory is preserved after WBI with mean dose rates …

Homer1a is a core brain molecular correlate of sleep loss

…, L Gurcel, S Pradervand, B Petit… - Proceedings of the …, 2007 - National Acad Sciences
… 1 A and B and suggest that very few genes show consistent changes in expression
across genetic backgrounds. We use the terms “consistent” and “reliable” hereafter only for …

Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type

…, M Travert, J Bosq, J Brière, B Petit… - Blood, The Journal …, 2010 - ashpublications.org
… express CD2, cytoplasmic CD3 (CD3ϵ chain), and CD56; are negative for CD5, CD4, and
CD8; and have a cytotoxic immunophenotype with expression of perforin, granzyme B (gzm B)…

Long-term follow-up of idiopathic ventricular fibrillation ablation: a multicenter study

…, M Wright, M Hocini, A Nogami, T Arentz, B Petit… - Journal of the American …, 2009 - jacc.org
… The origin of ventricular premature beat (VPB) triggering ventricular fibrillation (VF) was the
left Purkinje either at the posterior (A)or the anterior (B)insertion, the right Purkinje (C), and …