International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics
B Goldstein, B Giroir, A Randolph - Pediatric critical care …, 2005 - journals.lww.com
… b) What are the specific definitions of pediatric SIRS, infection, sepsis, severe sepsis, and
septic shock? c) What are the specific definitions of pediatric organ failure and the validity of …
septic shock? c) What are the specific definitions of pediatric organ failure and the validity of …
Type 2 diabetes: principles of pathogenesis and therapy
M Stumvoll, BJ Goldstein, TW Van Haeften - The Lancet, 2005 - thelancet.com
Type 2 diabetes mellitus has become an epidemic, and virtually no physician is without
patients who have the disease. Whereas insulin insensitivity is an early phenomenon partly …
patients who have the disease. Whereas insulin insensitivity is an early phenomenon partly …
Bipolar disorders
Bipolar disorders are a complex group of severe and chronic disorders that includes bipolar
I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder, …
I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder, …
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
…, JT Mendoza, KA Smith, J Caro, B Goldstein… - 2002 - jdc.jefferson.edu
BACKGROUND: Type 2 diabetes affects approximately 8 percent of adults in the United
States. Some risk factors--elevated plasma glucose concentrations in the fasting state and after …
States. Some risk factors--elevated plasma glucose concentrations in the fasting state and after …
Large-scale association analysis identifies new risk loci for coronary artery disease
Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
…, E Araki, PA Wilden, DA Cahill, BJ Goldstein… - Nature, 1991 - nature.com
SINCE the discovery of insulin nearly 70 years ago, there has been no problem more
fundamental to diabetes research than understanding how insulin works at the cellular level. …
fundamental to diabetes research than understanding how insulin works at the cellular level. …
Human epicardial adipose tissue is a source of inflammatory mediators
…, EA Keiper, AG Johnson, J Martin, BJ Goldstein… - Circulation, 2003 - Am Heart Assoc
Background— Inflammatory mediators that originate in vascular and extravascular tissues
promote coronary lesion formation. Adipose tissue may function as an endocrine organ that …
promote coronary lesion formation. Adipose tissue may function as an endocrine organ that …
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients …
The Canadian Network for Mood and Anxiety Treatments ( CANMAT ) previously published
treatment guidelines for bipolar disorder in 2005, along with international commentaries and …
treatment guidelines for bipolar disorder in 2005, along with international commentaries and …
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for …
… b Given the metabolic side effects, use should be carefully monitored. … b Or switch the SSRI
to another SSRI. c Or switch the SSRI or BUP to another SSRI or … Lactation risk category b …
to another SSRI. c Or switch the SSRI or BUP to another SSRI or … Lactation risk category b …
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects …
key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects …