User profiles for B. A. Connolly

Bryan Connolly

Eastern Connecticut State University
Verified email at easternct.edu
Cited by 706

Effect of noninvasive respiratory strategies on intubation or mortality among patients with acute hypoxemic respiratory failure and COVID-19: the RECOVERY-RS …

GD Perkins, C Ji, BA Connolly, K Couper, R Lall… - Jama, 2022 - jamanetwork.com
Importance Continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO)
have been recommended for acute hypoxemic respiratory failure in patients with COVID-19…

Zebularine: a novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases

L Zhou, X Cheng, BA Connolly, MJ Dickman… - Journal of molecular …, 2002 - Elsevier
Mechanism-based inhibitors of enzymes, which mimic reactive intermediates in the reaction
pathway, have been deployed extensively in the analysis of metabolic pathways and as …

Quadriceps wasting and physical inactivity in patients with COPD

…, RJ Tanner, JM Seymour, BA Connolly… - European …, 2012 - Eur Respiratory Soc
Quadriceps weakness is an important complication of advanced chronic obstructive
pulmonary disease (COPD) but few data exist concerning muscle bulk in early disease. We …

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

RJ Buchsbaum, BA Connolly… - Molecular and cellular …, 2002 - Am Soc Microbiol
Tiam1 and Ras-GRF1 are guanine nucleotide exchange factors (GEFs) that activate the
Rac GTPase. The two GEFs have similar N-terminal regions containing pleckstrin homology …

Structural basis for uracil recognition by archaeal family B DNA polymerases

MJ Fogg, LH Pearl, BA Connolly - Nature structural biology, 2002 - nature.com
Deamination of cytosine to uracil in a GC base pair is a major promutagenic event,
generating GC→AT mutations if not repaired before DNA replication. Archaeal family B DNA …

[HTML][HTML] Clinical predictive value of manual muscle strength testing during critical illness: an observational cohort study

BA Connolly, GD Jones, AA Curtis, PB Murphy… - Critical care, 2013 - Springer
Introduction Impaired skeletal muscle function has important clinical outcome implications for
survivors of critical illness. Previous studies employing volitional manual muscle testing for …

Chemical synthesis of oligonucleotides containing a free sulphydryl group and subsequent attachment of thiol specific probes

BA Connolly, P Rider - Nucleic Acids Research, 1985 - academic.oup.com
Oligonucleotides containing a free sulphydryl group at their 5′-termini have been synthesised
and further derivatised with thiol specific probes. The nucleotide sequence required is …

Underutilized chokeberry (Aronia melanocarpa, Aronia arbutifolia, Aronia prunifolia) accessions are rich sources of anthocyanins, flavonoids, hydroxycinnamic acids …

R Taheri, BA Connolly, MH Brand… - Journal of agricultural …, 2013 - ACS Publications
Polyphenols from underutilized black, purple, and red aronia ( Aronia melanocarpa , Aronia
prunifolia , and Aronia arbutifolia ) and ‘Viking’ ( Aronia mitschurinii ) berries were …

Effect of intermittent or continuous feed on muscle wasting in critical illness: a phase 2 clinical trial

AS McNelly, DE Bear, BA Connolly, G Arbane, L Allum… - Chest, 2020 - Elsevier
Connolly PhD f g , Gill Arbane BSc g , Laura Allum BSc g , Azhar Tarbhai BSc b , Jackie A.
Cooper MSc b , Philip A. Hopkins PhD h , Matthew P. …

A read-ahead function in archaeal DNA polymerases detects promutagenic template-strand uracil

…, G Panayotou, SJ Evans, BA Connolly… - Proceedings of the …, 1999 - National Acad Sciences
Deamination of cytosine to uracil is the most common promutagenic change in DNA, and it
is greatly increased at the elevated growth temperatures of hyperthermophilic archaea. If not …