User profiles for A. Tzouvelekis

Argyris Tzouvelekis

Associate Professor of Respiratory Medicine, University of Patras, greece
Verified email at upatras.gr
Cited by 5926

Idiopathic pulmonary fibrosis: Disease mechanisms and drug development

…, T Karampitsakos, TM Maher, A Tzouvelekis… - Pharmacology & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life and …

[HTML][HTML] Exploring animal models that resemble idiopathic pulmonary fibrosis

…, SJ Elliot, I Ninou, V Aidinis, A Tzouvelekis… - Frontiers in …, 2017 - frontiersin.org
Large multicenter clinical trials have led to two recently approved drugs for patients with
idiopathic pulmonary fibrosis (IPF); yet, both of these therapies only slow disease progression …

[HTML][HTML] Mechanisms of progressive fibrosis in connective tissue disease (CTD)-associated interstitial lung diseases (ILDs)

…, O Distler, CJ Ryerson, A Tzouvelekis… - Annals of the …, 2021 - ard.bmj.com
Interstitial lung diseases (ILDs), which can arise from a broad spectrum of distinct aetiologies,
can manifest as a pulmonary complication of an underlying autoimmune and connective …

Inhibition and role of let-7d in idiopathic pulmonary fibrosis

…, H Yousef, M Yarlagadda, A Tzouvelekis… - American journal of …, 2010 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal
fibrotic lung disease characterized by profound changes in epithelial cell phenotype and …

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function

G Yu, A Tzouvelekis, R Wang, JD Herazo-Maya… - Nature medicine, 2018 - nature.com
Thyroid hormone (TH) is critical for the maintenance of cellular homeostasis during stress
responses, but its role in lung fibrosis is unknown. Here we found that the activity and …

Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis

N Oikonomou, MA Mouratis, A Tzouvelekis… - American journal of …, 2012 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic form of diffuse lung disease
occurring mainly in older adults. Increased lysophosphatidic acid (LPA) concentrations …

Global Impairment of CD4+CD25+FOXP3+ Regulatory T Cells in Idiopathic Pulmonary Fibrosis

…, E Nakou, I Bouchliou, A Tzouvelekis… - American journal of …, 2009 - atsjournals.org
Rationale: The implication of T cells in the pathogenesis of idiopathic pulmonary fibrosis (IPF)
is controversial. CD4 + CD25 + FOXP3 + regulatory T cells (Tregs) are pivotal in …

Lung cancer in patients with idiopathic pulmonary fibrosis

…, V Aidinis, SA Papiris, D Bouros, A Tzouvelekis - Pulmonary …, 2017 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease of unknown etiology. With
a gradually increasing worldwide prevalence and a mortality rate exceeding that of many …

[HTML][HTML] Precision medicine advances in idiopathic pulmonary fibrosis

T Karampitsakos, BM Juan-Guardela, A Tzouvelekis… - …, 2023 - thelancet.com
Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous, unpredictable and ultimately
lethal chronic lung disease. Over the last decade, two anti-fibrotic agents have been shown to …

Idiopathic pulmonary fibrosis: an update

…, G Rossi, A Cavazza, A Tzouvelekis… - Annals of …, 2015 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic interstitial
pneumonia. The disease, which occurs primarily in middle-aged and older adults, is …