[HTML][HTML] Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice

…, FC Weisel, K Milger, B Egemnazarov, A Turowska… - Cell, 2011 - cell.com
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death
worldwide. We report in an emphysema model of mice chronically exposed to tobacco …

[HTML][HTML] Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme

…, J Bille, U Homburg, A Turowska… - … England Journal of …, 2015 - Mass Medical Soc
Background The most prevalent phenotype of asthma is characterized by eosinophil-dominated
inflammation that is driven by a type 2 helper T cell (Th2). Therapeutic targeting of …

Amphiphilic Biodegradable PEG-PCL-PEI Triblock Copolymers for FRET-Capable in Vitro and in Vivo Delivery of siRNA and Quantum Dots

T Endres, M Zheng, A Kılıç, A Turowska… - Molecular …, 2014 - ACS Publications
Amphiphilic triblock copolymers represent a versatile delivery platform capable of co-delivery
of nucleic acids, drugs, and/or dyes. Multifunctional cationic triblock copolymers based on …

Rectal delivery of a DNAzyme that specifically blocks the transcription factor GATA3 and reduces colitis in mice

V Popp, K Gerlach, S Mott, A Turowska, H Garn… - Gastroenterology, 2017 - Elsevier
Background & Aims GATA3 is a transcription factor that regulates T-cell production of
cytokines. We investigated the role of GATA3 in development of colitis in mice. Methods We …

Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma

…, O Schmidt, J Kuhlmann, A Turowska… - Journal of Allergy and …, 2015 - jacionline.org
LETTERS TO THE EDITOR 797 possible, the observed events might also correspond to
mucosal irritation caused by inhalation of the nebulizer formulation. Other respiratory complaints …

Effect of TIG welding and rare earth elements alloying on corrosion resistance of magnesium alloys

…, DS Kharitonov, J Adamiec, A Turowska - Journal of The …, 2020 - iopscience.iop.org
The corrosion resistance of the welds made of QE22, ZRE1, and WE43 rare-earth-metals-containing
magnesium alloys was investigated in 0.5% NaCl solution saturated with Mg (OH) 2 …

Biodistribution of the GATA-3-specific DNAzyme hgd40 after inhalative exposure in mice, rats and dogs

A Turowska, D Librizzi, N Baumgartl… - Toxicology and applied …, 2013 - Elsevier
The DNAzyme hgd40 was shown to effectively reduce expression of the transcription factor
GATA-3 RNA which plays an important role in the regulation of Th2-mediated immune …

Toxicity profile of the GATA-3-specific DNAzyme hgd40 after inhalation exposure

…, T Hansen, J von Erichsen, A Turowska… - Pulmonary …, 2013 - Elsevier
DNAzymes are single-stranded catalytic DNA molecules that bind and cleave specific
sequences in a target mRNA molecule. Their potential as novel therapeutic agents has been …

[HTML][HTML] Comparison of safety of radial and femoral approaches for coronary catheterization in interventional cardiology

W Samul, A Turowska, PJ Kwasiborski… - … medical journal of …, 2015 - ncbi.nlm.nih.gov
Background The femoral approach has been the preferably used access in interventional
cardiology as well for coronary diagnostics as for percutaneous coronary intervention, being …

Visceral fat level correction of the left ventricular hypertrophy electrocardiographic criteria

S Salamaga, F Dydowicz, A Turowska… - Annals of …, 2021 - Wiley Online Library
Background Left ventricular hypertrophy (LVH) is a well‐known risk factor for cardiovascular
events. Even though there are many electrocardiographic (ECG) criteria for LVH, they still …