[HTML][HTML] Inherited resistance to HIV-1 conferred by an inactivating mutation in CC chemokine receptor 5: studies in populations with contrasting clinical phenotypes …
…, C Combadiere, D Weissman, O Cohen, A Rubbert… - Molecular …, 1997 - Springer
Background CC chemokine receptor 5 (CCR5) is a cell entry cofactor for macrophage-tropic
isolates of human immunodeficiency virus-1 (HIV-1). Recently, an inactive CCR5 allele (…
isolates of human immunodeficiency virus-1 (HIV-1). Recently, an inactive CCR5 allele (…
Natural killer cells from human immunodeficiency virus (HIV)-infected individuals are an important source of CC-chemokines and suppress HIV-1 entry and replication …
…, AL Kinter, M Vaccarezza, A Rubbert… - The Journal of …, 1998 - Am Soc Clin Investig
Macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES (regulated on
activation, normal T cell expressed and secreted), which are the natural ligands of the CC-…
activation, normal T cell expressed and secreted), which are the natural ligands of the CC-…
Discovery of the ergothioneine transporter
…, R Berkels, N Jung, A Rubbert… - Proceedings of the …, 2005 - National Acad Sciences
Variants of the SLC22A4 gene are associated with susceptibility to rheumatoid arthritis and
Crohn's disease. SLC22A4 codes for an integral membrane protein, OCTN1, that has been …
Crohn's disease. SLC22A4 codes for an integral membrane protein, OCTN1, that has been …
The registry of the German Network for Systemic Scleroderma: frequency of disease subsets and patterns of organ involvement
…, M Weber, M Worm, P Klaus, A Rubbert… - …, 2008 - academic.oup.com
Objective. Systemic sclerosis (SSc) is a rare, heterogeneous disease, which affects different
organs and therefore requires interdisciplinary diagnostic and therapeutic management. To …
organs and therefore requires interdisciplinary diagnostic and therapeutic management. To …
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update
…, C Richez, P Van Riel, A Rubbert-Roth… - Annals of the …, 2017 - ard.bmj.com
Recent insights in rheumatoid arthritis (RA) necessitated updating the European League
Against Rheumatism (EULAR) RA management recommendations. A large international Task …
Against Rheumatism (EULAR) RA management recommendations. A large international Task …
Relevance of the organic cation transporters 1 and 2 for antiretroviral drug therapy in human immunodeficiency virus infection
N Jung, C Lehmann, A Rubbert, M Knispel… - Drug Metabolism and …, 2008 - ASPET
Carrier-mediated transport across cell membranes is an important determinant of activity,
resistance, and toxicity of chemotherapeutic agents including antiretroviral (ARV) drugs (ARDs)…
resistance, and toxicity of chemotherapeutic agents including antiretroviral (ARV) drugs (ARDs)…
Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
D Weissman, RL Rabin, J Arthos, A Rubbert, M Dybul… - Nature, 1997 - nature.com
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) enter target
cells by forming a complex between the viral envelope protein and two cell-surface …
cells by forming a complex between the viral envelope protein and two cell-surface …
HIV-1 envelope induces activation of caspase-3 and cleavage of focal adhesion kinase in primary human CD4+ T cells
C Cicala, J Arthos, A Rubbert, S Selig… - Proceedings of the …, 2000 - National Acad Sciences
Binding of HIV type 1 (HIV-1) envelope glycoproteins to the surface of a CD4 + T cell
transduces intracellular signals through the primary envelope receptor, CD4, and a coreceptor, …
transduces intracellular signals through the primary envelope receptor, CD4, and a coreceptor, …
Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry
A Rubbert, C Combadiere, M Ostrowski… - The Journal of …, 1998 - journals.aai.org
Cells of the dendritic lineage are thought to be among the first cells infected after mucosal
exposure to HIV. In this study, we have identified the presence of multiple chemokine …
exposure to HIV. In this study, we have identified the presence of multiple chemokine …
[HTML][HTML] Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review
A Rubbert-Roth, A Finckh - Arthritis research & therapy, 2009 - Springer
Conventional disease-modifying antirheumatic drugs such as methotrexate are the mainstay
of treatment for rheumatoid arthritis. More recently, biologic agents such as etanercept, …
of treatment for rheumatoid arthritis. More recently, biologic agents such as etanercept, …