Mesenchymal stem cells (MSC) are multipotent cells that differentiate into osteoblasts,
myocytes, chondrocytes and adipocytes as well as insulin-producing cells. The mechanism …

There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …

Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes.
Telomere length is a marker of DNA damage, which is often considered a biomarker for …

The aim of this study was to develop a pH-sensitive chitosan/polyvinyl pyrrolidone (PVP) based
controlled drug release system for antibiotic delivery. The hydrogels were synthesised by …

Insulin-expressing beta cells, found in pancreatic islets, are capable of generating more beta
cells even in the adult. We show that fibroblast-like cells derived from adult human islets …

During pancreatic islet development, sequential changes in gene expression are known to
be necessary for efficient differentiation and function of the endocrine pancreas. Several …

Development of the endocrine pancreas includes a series of early events wherein precursor
cells cluster, that is migrate to form cell aggregates, which subsequently differentiate into …

The mammalian pancreas is known to show a remarkable degree of regenerative ability.
Several studies until now have demonstrated that the mammalian pancreas can regenerate in …

The ability to detect glucose concentrations in human urine offers a non-invasive approach
to monitor changes in blood glucose, kidney health and vascular complications associated …

Epithelial-to-mesenchymal transition is a phenomenon necessary for embryonic development
and also seen during certain pathological conditions. We show here for the first time that …