Current state-of-the-art biomedical implants and tissue engineering methods promise
technologies to improve or even restore the function of diseased organs. However, one of the …

Highlights • Microfluidics enables fabrication of drug carriers with controlled geometry and
release profile. • Microfluidic platforms enable effective localized drug delivery at cell, tissue, …

Macrophages are key players in many physiological scenarios including tissue homeostasis.
In response to injury, typically the balance between macrophage sub-populations shifts …

Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels
used to support epidermal regeneration are mainly collagen‐ or gelatin‐based, which …

Fabrication of three dimensional (3D) organoids with controlled microarchitectures has been
shown to enhance tissue functionality. Bioprinting can be used to precisely position cells …

Surgical adhesive biomaterials have emerged as substitutes to sutures and staples in many
clinical applications. Nano-enabled materials containing nanoparticles or having a distinct …

The mannose receptor (MR) is a C-type lectin expressed by dendritic cells (DCs). We have
investigated the ability of MR to recognize glycosylated allergens. Using a gene silencing …

Adverse immune reactions prevent clinical translation of numerous implantable devices and
materials. Although inflammation is an essential part of tissue regeneration, chronic …

Macrophages play a central role in orchestrating immune responses to foreign materials,
which are often responsible for the failure of implanted medical devices. Material topography is …

Here, we present a physiologically relevant model of the human pulmonary alveoli. This
alveolar lung-on-a-chip platform is composed of a three-dimensional porous hydrogel made of …