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Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs.
Danov O, Jiménez Delgado SM, Obernolte H, Seehase S, Dehmel S, Braubach P, Fieguth HG, Matschiner G, Fitzgerald M, Jonigk D, Knauf S, Pfennig O, Warnecke G, Wichmann J, Braun A, Sewald K. Danov O, et al. Among authors: pfennig o. PLoS One. 2018 Nov 30;13(11):e0207767. doi: 10.1371/journal.pone.0207767. eCollection 2018. PLoS One. 2018. PMID: 30500834 Free PMC article.
Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices.
Switalla S, Lauenstein L, Prenzler F, Knothe S, Förster C, Fieguth HG, Pfennig O, Schaumann F, Martin C, Guzman CA, Ebensen T, Müller M, Hohlfeld JM, Krug N, Braun A, Sewald K. Switalla S, et al. Among authors: pfennig o. Toxicol Appl Pharmacol. 2010 Aug 1;246(3):107-15. doi: 10.1016/j.taap.2010.04.010. Epub 2010 Apr 29. Toxicol Appl Pharmacol. 2010. PMID: 20434477
Assessment of long-term cultivated human precision-cut lung slices as an ex vivo system for evaluation of chronic cytotoxicity and functionality.
Neuhaus V, Schaudien D, Golovina T, Temann UA, Thompson C, Lippmann T, Bersch C, Pfennig O, Jonigk D, Braubach P, Fieguth HG, Warnecke G, Yusibov V, Sewald K, Braun A. Neuhaus V, et al. Among authors: pfennig o. J Occup Med Toxicol. 2017 May 26;12:13. doi: 10.1186/s12995-017-0158-5. eCollection 2017. J Occup Med Toxicol. 2017. PMID: 28559920 Free PMC article.