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Combination of the novel farnesyltransferase inhibitor RPR130401 and the geranylgeranyltransferase-1 inhibitor GGTI-298 disrupts MAP kinase activation and G(1)-S transition in Ki-Ras-overexpressing transformed adrenocortical cells.
Mazet JL, Padieu M, Osman H, Maume G, Mailliet P, Dereu N, Hamilton AD, Lavelle F, Sebti SM, Maume BF. Mazet JL, et al. Among authors: padieu m. FEBS Lett. 1999 Oct 29;460(2):235-40. doi: 10.1016/s0014-5793(99)01355-1. FEBS Lett. 1999. PMID: 10544242 Free article.