Gadofosveset-enhanced lung magnetic resonance imaging to detect ongoing vascular leak in pulmonary fibrosis

Eur Respir J. 2018 May 17;51(5):1800171. doi: 10.1183/13993003.00171-2018. Print 2018 May.

¹ Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
² Dept of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
³ Division of Pulmonary, Critical Care and Sleep Medicine, Albert Medical School of Brown University, Providence, RI, USA.
⁴ Siemens Healthcare, Boston, MA, USA.
⁵ Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
⁶ Institute for Innovation in Imaging, Massachusetts General Hospital, Charlestown, MA, USA.

Abstract

Vascular leak is increased diffusely in the lungs in pulmonary fibrosis and is not limited to radiographic areas of disease involvement.