Abstract
Experimental studies helped to reveal ultrastructural changes in hepatocytes, caused by prolonged exposure to heavy metals salts taken in combination and ratios characteristic to soil contents near Almalyk mining and smelting enterprise. The authors demonstrated possibility of liver structural recovery via enterosorption with additional antioxidant therapy.
MeSH terms
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Animals
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Antioxidants / administration & dosage
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Antioxidants / therapeutic use*
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Chemical and Drug Induced Liver Injury / metabolism
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Chemical and Drug Induced Liver Injury / pathology
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Chemical and Drug Induced Liver Injury / prevention & control
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Enterosorption / methods*
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Hepatocytes / drug effects
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Hepatocytes / metabolism
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Hepatocytes / ultrastructure
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Lipid Peroxidation / drug effects
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Liver / drug effects*
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Liver / metabolism
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Liver / ultrastructure*
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Metals, Heavy / toxicity*
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Microscopy, Electron, Transmission
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Plant Extracts / administration & dosage
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Plant Extracts / therapeutic use
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Rats
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Salts
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Soil Pollutants / toxicity*
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Time Factors
Substances
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Antioxidants
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Metals, Heavy
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Plant Extracts
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Salts
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Soil Pollutants